Results 111 to 120 of about 26,924 (226)

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

Food Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Surgical Management of Gynecomastia—a 10-year Analysis [PDF]

, 2018
Background: Gynecomastia is defined as the benign enlargement of the male breast. Most studies on surgical treatment of gynecomastia show only small series and lack histopathology results. The aim of this study was to analyze the surgical approach in the
Banic, A., Bietry, D., Constantinescu, M., Handschin, A., Hüsler, R.   +4 more
core  

Exploring the Potential of Tsuruazuki Bean as a Functional Food to Curb Obesity Using Human Amniotic Epithelial Cells and 3T3‐L1 Preadipocytes

Food Frontiers, EarlyView.
Obesity is a global health problem that requires research and regulatory attention. This research aims to investigate transcriptome‐wide changes induced by Vigna umbellata (Tsuruazuki) using a stem cell‐based tool and preadipocytes to explore its untapped potential as a functional food for anti‐obesity applications.
Elda Nurafnie Ibnu Rasid, Farhana Ferdousi, Kazunori Sasaki, Kyoko Toda, Shinya Takahashi, Mari Maeda‐Yamamoto, Hiroko Isoda   +6 more
wiley   +1 more source

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. [PDF]

, 2019
Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations
Aldahl, Joseph, Cardiff, Robert D, Geradts, Joseph, He, Yongfeng, Hooker, Erika, Johnson, Daniel T, Kim, Won Kyung, Le, Vien, Lee, Dong-Hoon, Sun, Zijie, Wu, Huiqing, Yang, Julie S, Yoon, Junhee, You, Sungyong, Yu, Eun-Jeong   +14 more
core  

The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Hawthorn: A Review

Food Frontiers, EarlyView.
This review systematically and comprehensively analyzes hawthorn (Crataegus spp.), covering its bioactive constituents, properties, and processed products. ABSTRACT Hawthorn is widely cultivated in China, with excellent varieties and steadily increasing production.
Wenteng Yang, Quanhong Gao, Kun Ran, Mingyue Jiao, Xiaodan Fu, Zhenlin Han, Chao Liu, Ningyang Li   +7 more
wiley   +1 more source

Impact of Endocrine‐Disrupting Chemicals (EDCs) Used in the Food Industry on Endocrine Abnormalities

Food Safety and Health, EarlyView.
This review was conducted to examine the relationship between hormone disruption and other endocrine abnormalities in the context of the constant consumption of genetically modified foods and overexposure to chemicals used directly and indirectly in the agrifood industry.
Perla D. Serrano‐López, Frida B. Ocampo‐Juárez, Alexandra Magaña‐Rodríguez, José A. Téllez‐Morales   +3 more
wiley   +1 more source

Infiltrating syringomatous adenoma of nipple [PDF]

, 2008
Infiltrating syringomatous adenoma of the nipple is a rare, benign lesion with distinct clinical and histological features. Origin from ducts of dermal sweat glands has been postulated.
Idress, Romana, Kayani, Naila, Khan, Shaista Masood, Riaz, Nazia   +3 more
core   +1 more source

Comparative single‐cell analysis of esophageal cancer subtypes reveals tumor microenvironment distinctions explaining varied immunotherapy responses

Cancer Communications, EarlyView.
Seungbyn Baek, Junha Cha, Min Hee Hong, Gamin Kim, Yoon Woo Koh, Dahee Kim, Wonrak Son, Chan‐Young Ock, Seungeun Lee, Martin Hemberg, Seong Yong Park, Hye Ryun Kim, Insuk Lee   +12 more
wiley   +1 more source

Late Toxicity and Long‐Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi‐National Study

Head &Neck, EarlyView.
ABSTRACT Background Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long‐term quality of life and late toxicities are sparse. Methods Multi‐national study including SGC survivors more than 5 years after diagnosis.
Susanne Singer, Cecilie Delphin Amdal, Kristin Bjordal, Bente Brokstad Herlofson, Guro Lindviksmoen Astrup, Andreas Boehm, Ulrike Wöhner, Eva Hammerlid, Ricardo Ribeiro Gama, Alexandre Arthur Jacinto, Femke Jansen, Irma Verdonck de Leeuw, Tatiana Dragan, Fréderic Duprez, Naomi Kiyota, Monica Pinto, Maximilian Krüger, Orlando Guntinas‐Lichius, Johanna Inhestern, Francesco Tramacere, Pierluigi Bonomo, Giuseppe Fanetti, Sandra Nuyts, Michaela Plath, Noa Stempler, Kristine Løken Westgaard, Katherine J. Taylor   +26 more
wiley   +1 more source

Application of a Saliva‐Based Liquid Biopsy for the Detection of HPV in Patients With Oral Cavity Squamous Cell Carcinoma (OCSCC)

Head &Neck, EarlyView.
ABSTRACT Background Human papilloma virus (HPV) is a DNA virus capable of infecting mucous membranes. In most cases, the infection is cleared by the immune system, but a prolonged exposure to HPV can progress to cancer. 40%–60% of head and neck squamous cell carcinomas (HNSCC) are linked to HPV, which is considered a risk factor especially among young ...
Michela Bulfoni, Alessandro Tel, Beatrice Krpan, Barbara Marcon, Maria De Martino, Giorgia Vesca, Cinzia Lombardo, Stefania Marzinotto, Emanuele Nencioni, Salvatore Sembronio, Corrado Pipan, Massimo Robiony, Francesco Curcio   +12 more
wiley   +1 more source