Results 111 to 120 of about 44,661 (225)

Noninvasive Detection and Thermal Ablation Therapy of Endometriosis Using Silica‐Coated Gold Nanorods

Advanced NanoBiomed Research, EarlyView.
AuNR@Si(F)‐PEG nanoparticles are developed as theranostic agents for the noninvasive detection and photothermal therapy of endometriosis. The particles are preferentially taken up by the endometriosis lesions under photoacoustic image‐guidance, and used as thermal ablation therapeutics to shrink the lesions.
Panangattukara Prabhakaran Praveen Kumar, Seock‐Jin Chung, Kay Hadrick, Meghan L. Hill, Maggie Lee, Tae Hoon Kim, Jae‐Wook Jeong, Taeho Kim   +7 more
wiley   +1 more source

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

The Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Transitional cell carcinoma of suspected ureteral origin, with intra-abdominal and distant metastases in two horses [PDF]

, 2011
The present paper describes two cases of suspected urothelial carcinomas with local lymphatic metastases, and distant metastases in the lungs. In one case, liver metastases were also present.
De Clercq, Dominique, Deprez, Piet, Ducatelle, Richard, Maes, Sofie, Martens, Ann, Saey, Veronique, Torfs, Sara, van Loon, Gunther, Vercauteren, Griet   +8 more
core   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

Animal Research and One Health, EarlyView.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang, Ao Guo, Lin Zhang, Shengru Wu, Juan Du, Taiyong Yu   +5 more
wiley   +1 more source

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. [PDF]

, 2019
Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations
Aldahl, Joseph, Cardiff, Robert D, Geradts, Joseph, He, Yongfeng, Hooker, Erika, Johnson, Daniel T, Kim, Won Kyung, Le, Vien, Lee, Dong-Hoon, Sun, Zijie, Wu, Huiqing, Yang, Julie S, Yoon, Junhee, You, Sungyong, Yu, Eun-Jeong   +14 more
core  

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

Arthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

Cancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang, Zhen Qin, Xiu‐Wu Bian, Yu Shi   +3 more
wiley   +1 more source

What is new in Genitourinary Pathology? Recent developments and highlights of the new 2016 World Health Organization classification of tumors of the urinary system and male genital organs [PDF]

, 2016
Daniel Abensur Athanazio, Kiril Trpkov
core   +1 more source