Results 21 to 30 of about 42,041 (231)

Mapping of succinate dehydrogenase losses in 2258 epithelial neoplasms. [PDF]

, 2014
Losses in the succinate dehydrogenase (SDH) complex characterize 20% to 30% of extra-adrenal paragangliomas and 7% to 8% of gastric GISTs, and rare renal cell carcinomas.
McCue, Peter, Czapiewski, Piotr, Wazny, Krzysztof, Miettinen, Markku, Langfort, Renata, Lasota, Jerzy, Wang, Zengfeng, Sarlomo-Rikala, Maarit, Biernat, Wojciech, Waloszczyk, Piotr   +9 more
core   +1 more source

Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?

Dermatology Practical & Conceptual, 2012
Analogous to adenomyoepitheliomas of the breast, cutaneous adenomyoepithelioma is composed of two components, one being myoepithelial, the other ductal epithelial, and it lies in the spectrum of neoplasms having a “pure” myoepithelioma at one end and a ...
Elisabeth Reidl, Geoffrey J. Gottlieb
doaj   +1 more source

Urachal mucinous neoplasms--to be or not to be: Two cases and a review of current diagnostic criteria (WHO 2016)

, 2018
The urachus is an embryological remnant that extends from the bladder to the umbilicus. Urachal neoplasms represent less than 1% of malignant bladder tumors.
Isabel Hierro, Isabel García, Lidia Pérez, Bernardo Herrera, Luis Vicioso, Juan Daniel Prieto Cuadra, Martina Álvarez   +6 more
core   +1 more source

First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427)

Contemporary Clinical Trials Communications, 2019
Background: MYB is a transcription factor that is overexpressed in colorectal cancer (CRC) and also a driver mutation in adenoid cystic carcinoma (AdCC).
Toan Pham, Lloyd Pereira, Sara Roth, Laura Galletta, Emma Link, Tim Akhurst, Ben Solomon, Michael Michael, Phillip Darcy, Shienny Sampurno, Alexander Heriot, Robert Ramsay, Jayesh Desai   +12 more
doaj   +1 more source

Expression of E-cadherin, cellular differentiation and polarity in epithelial salivary neoplasms

, 2000
To investigate whether expression of E-cadherin correlates with polarised tissue organisation, grade or tumour type in salivary neoplasms, frozen sections from 30 salivary gland neoplasms were stained immunohistochemically for E-cadherin using the ...
Hanby, A, Economopoulou, P, Odell, E W
core   +1 more source

Blastomatoid pulmonary carcinosarcoma: report of a case with a review of the literature

BMC Cancer, 2012
Background Pulmonary carcinosarcoma is a biphasic tumour with an unfavourable prognosis. The differential diagnosis includes pulmonary blastoma and is often challenging.
Schaefer Inga-Marie, Sahlmann Carsten-Oliver, Overbeck Tobias, Schweyer Stefan, Menke Jan   +4 more
doaj   +1 more source

Exploring functional mechanisms underlying tumor initiation, EMT and cell migration [PDF]

, 2012
Cancer is one of the leading causes of death. A primary tumor forms when cells start to proliferate in an uncontrolled way and stop reacting to restraining signals.
Gruber, Dorothea Cornelia
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source