Results 31 to 40 of about 46,655 (248)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Consensus guidelines for the management of craniopharyngioma in low- and middle-income countries

Journal of the Pakistan Medical Association
Craniopharyngiomas are benign, extra-axial epithelial tumours originating from the pituitary stalk, impacting areas such as the hypothalamus, optic chiasm, and various cranial nerves.
Syed Ather Enam, Naureen Mushtaq, Muhammad Usman Khalid, Mohammad Hamza Bajwa, Ahsan Ali Khan, Sehar Salim Verani, Anam Tariq, Ahmed Gilani, Bilal Mazhar Qureshi, Pakistan Brain Tumour Consortium: Authors list at the end of the supplement.   +9 more
doaj   +1 more source

Nonintestinal-Type Sinonasal Adenocarcinoma

Philippine Journal of Otolaryngology Head and Neck Surgery, 2009
Malignant glandular neoplasms of the sinonasal tract originate either from the respiratory epithelium or the underlying mucoserous glands. They present with a confusing array of morphologic features and this is reflected in the nomenclature of these ...
Jose M. Carnate
doaj   +1 more source

Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]

, 2017
Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco, DE VIRGILIO, Armando, Fusconi, Massimo, Gallo, Andrea, Greco, Antonio, Martellucci, Salvatore, Pagliuca, Giulio   +6 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation [PDF]

, 2011
Metaplastic breast carcinoma is very rare neoplasm which contains mixture of carcinomatous (epithelial) and sarcomatous (mesenchymal) elements in variable proportion. Metaplastic carcinoma with chondroid differentiation is even rarer.
Bohra, Ashish, Jagtap, Sunil V, Jain, Gaurav, Kanetkar, Sujata R, Nikumbh, Dhiraj B   +4 more
core   +1 more source

Müllerian Adenosarcoma of the Urinary Bladder: Clinicopathologic and Immunohistochemical Features with Novel Genetic Aberrations [PDF]

, 2017
Müllerian adenosarcoma is a biphasic neoplasm most commonly of the uterus and less frequently of the ovary. It has been rarely described to occur in other sites such as peritoneum and liver.
Cheng, Liang, Gardner, Thomas A., Kum, Jennifer B., Lopez-Beltran, Antonio, Montironi, Rodolfo, Sanfrancesco, Joseph, Wang, Mingsheng, Williamson, Sean R., Zhang, Shaobo   +8 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Squamous cell carcinoma arising from chronic lymphedema: case report and review of the literature

São Paulo Medical Journal
CONTEXT: Squamous cell carcinoma arising from chronic lymphedema has only been reported in the literature 11 times (12 cases). Some aspects of its pathogenesis remain unclear and, for the first time, attention has been drawn to epidemiological data. CASE
Carlos Augusto Gomes, Camila Beatriz Silva Magalhães, Cleber Soares Junior, Rodrigo de Oliveira Peixoto   +3 more
doaj   +1 more source

Prevalence of precancerous and cancerous cervical lesions in women from Batna, Algeria [PDF]

Epidemiology and Health System Journal
Background and aims: Cervical cancer is the fourth most frequently diagnosed cancer among Algerian women and the seventh in Batna. This study sought to evaluate the prevalence of precancerous and cancerous cervical lesions and identify the target age ...
Waffa Bouafia, Abdelmoudjib Ghecham, Rachid Benslitane   +2 more
doaj   +1 more source