Results 61 to 70 of about 939,582 (302)

Multiple metachronous and synchronous malignancies with lung and thorax involvement. Report of two cases

Respiratory Medicine Case Reports, 2018
Multiple primary malignant neoplasms (MPMN) is an uncommon phenomenon, while the diagnosis of such conditions is very significant. Considering that the strategy of the treatment is determined by the histological type of the tumor, practitioners should be
Konstantinos Sapalidis, Nikos Schizas, Achileas Lazopoulos, Parthena Kamparoudi, Dimitris Paliouras, Chrysa Sardeli, Fotis Konstantinou, Fotis Chatzinikolaou, Pavlos Sarafis, Paul Zarogoulidis, Ioanna Kougioumtzi, Nikolaos Katsikogiannis, Ilias Karapantzos, Chrysa Karapantzou, Stella Laskou, Charilaos Koulouris, Stylianos Mantalobas, Dimitris Giannakidis, Isaak Kesisoglou, Nikos Barbetakis   +19 more
doaj   +1 more source

Characteristics of Multiple Primary Malignant Neoplasms Associated with the Urinary Tract Malignancy [PDF]

, 2001
Purpose: Improvement in the prognosis of multiple primary malignant neoplasm may be attained by early discovery and awareness of the secondary tumor. This study aimed to determine the characteristics of multiple primary neoplasms involving the urinary ...
최영득
core  

Multiple primary malignancies

, 2004
As the incidence and prevalence of cancer increase with age, it is reasonable to expect that the incidence and prevalence of multiple primary malignancies will increase as well.
A. Luciani, L. Balducci
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Neoplasias primárias múltiplas em pacientes com câncer colorretal Multiple primary neoplasms in colorectal cancer patients

, 2000
Introdução - A presença de uma segunda neoplasia maligna, tendo sítio e histologia diferentes da primeira, define o conceito de neoplasias primárias múltiplas.
Marcelo de Souza CURY, Cury, Marcelo De Souza [UNIFESP], Nora Manoukian FORONES, Forones, Nora Manoukian [UNIFESP], CURY, Marcelo de Souza, FORONES, Nora Manoukian   +5 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Analysis of the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in a general hospital

Бюллетень сибирской медицины
Aim. To analyze the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in 2017–2023 in a multidisciplinary inpatient facility.Materials and methods.
M. V. Zavyalova, A. V. Zavyalov, D. S. Pismenny, L. V. Pikalova, L. D. Zhuykova, Yu. M. Zhuykova, M. Yu. Grishchenko, S. V. Vtorushin, N. V. Litvyakov, M. V. Perelmuter   +9 more
doaj   +1 more source

Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck

, 2006
Background The proto-oncogene pituitary tumor-transforming gene (PTTG) has been shown to be abundantly overexpressed in a large variety of neoplasms likely promoting neo-vascularization and tumor invasiveness.
Solbach, Christine, Peters Silke, Eckerdt, Frank, Peters, Silke, Knecht, Rainald, Roller, Marc, Roller Marc, Eckerdt Frank, Solbach Christine, Knecht Rainald   +9 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source