Results 141 to 150 of about 1,398,433 (359)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Significance of GRP78 expression in acute myeloid leukemias
Wróbel Tomasz+7 more
doaj +1 more source
Background Organoids are approved by the US FDA as an alternative to animal experiments to guide drug development and for sensitivity screening. Stable organoids models of gastric cancer are desirable for personalized medicine and drug screening. Methods
Ruixin Yang+13 more
doaj +1 more source
Induction of mammary neoplasms in the ACI rat by 430-keV neutrons, X-rays, and diethylstilbestrol [PDF]
Chmelevsky, D.+4 more
core +1 more source
Lipoleiomyoma of the Uterus [PDF]
Lipoleiomyomas are uncommon benign neoplasms of uterus consisting of variable portions of mature lipocytes and smooth muscle cells. These tumours generally occur in asymptomatic obese perimenopausal or menopausal women.
Alper, Murat+4 more
core
Spontaneous neoplasms in fishes. V. Acinar adenocarcinoma of the pancreas in a hybrid platyfish
Ross F. Nigrelli, Myron Gordon
openalex +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
A NEOPLASM OF MONOCYTES OF MICE AND ITS RELATION TO SIMILAR NEOPLASMS OF MAN [PDF]
J. Fürth
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source