Results 101 to 110 of about 2,212,728 (310)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Pathogenesis of Warthin’s Tumor: Neoplastic or Non-Neoplastic?

Cancers
Warthin’s tumor is the second most frequent neoplasm next to pleomorphic adenoma in the salivary gland, mostly in the parotid gland. The epithelial cells constituting a tumor are characterized by the presence of mitochondria that undergo structural and functional changes, resulting in the development of oncocytes.
Ryogo Aoki, Takuji Tanaka
openaire   +2 more sources

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Evaluation of the Histomorphological Analysis of Testicular Lesions [PDF]

International Journal of Scientific Research in Dental and Medical Sciences
Background and aim: The normal adult testis is a paired organ in the scrotum, suspended by the spermatic cord. Both non-neoplastic and neoplastic conditions can impact it.
Minal Jain, Gunja Dwivedi, Ravi Sharma, Nilam Charaniya   +3 more
doaj   +1 more source

MUC4 expression in non-neoplastic urothelium and various malignant phenotypes of bladder.

, 2014
acomparison vs. non-neoplastic urothelium.bp≤0.0001 vs. non-neoplastic urothelium.cp≤0.005 vs.
Sukhwinder Kaur (91168), Subhankar Chakraborty (230378), Adam J. Horn (543028), Subodh M. Lele (122057), David G. Wagner (543027), Dan Theodorescu (105547), Navneet Momi (543026), Surinder K. Batra (120446)   +7 more
core   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

Advanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet, Charles Handschin, Theo Desigaux, Nathalie Dusserre, Marie‐Laure Stachowicz, Shane Fennell, Malou Lea, Silvia Arcucci, Benoît Thibault, Jean‐Christophe Fricain, Julie Guillermet‐Guibert, Hugo Oliveira   +11 more
wiley   +1 more source

Classification of neoplastic and non-neoplastic cystic lesions in ovaries [PDF]

, 2011
Classification of Neoplastic and Non-neoplastic Cystic Lesions in Ovaries Purpose: Determination of the rates of neoplastic and non-neoplastic lesions in ovary cyst cases having been operated.
Turhan, Ebru, Hakverdi, Sibel, Dolapçıoğlu, Kenan Serdar, Baloğlu, Ali, Benk Şilfeler, Dilek, Erdem, Duygu, Güngören, Arif, Hakverdi, Ali Ulvi   +7 more
core  

Raman spectroscopy for classification of neoplastic and non-neoplastic CAM colon tumors [PDF]

This paper demonstrates the potential of Raman spectroscopy for differentiating neoplastic from non-neoplastic colon tumors, obtained with the CAM (chicken chorioallantoic membrane) model.
M.J. Maciel, M.F. Cerqueira, C.A. Silva, S. Pimenta, F. Baltazar, P. Alpuim, J.H. Correia, M. Costa, B. Esteves, Correia, J.H., Cerqueira, M. F., Alpuim, P., Silva, C.A., Maciel, M.J., Costa, M., Correia, J. H., Pimenta, Sara Filomena Ribeiro, Maciel, Marino Jesus Correia, Pimenta, S., Baltazar, Fátima, Esteves, Bruno Miguel Carpinteiro, Baltazar, F., Costa, Marta Sílvia Freitas, Silva, Carlos A., Esteves, B., Cerqueira, M.F.   +25 more
core   +1 more source