Results 121 to 130 of about 617,302 (345)
Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Advanced Science, EarlyView.Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska +18 more
wiley +1 more source
THE DISTRIBUTION OF DEOXYRIBONUCLEASE IN NORMAL, CIRRHOTIC AND NEOPLASTIC RAT LIVERS [PDF]
, 1959 R. Daoust, Antonio Cantero
openalex +1 more source
Advanced Science, EarlyView.Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu +20 more
wiley +1 more source
Detection of Antigens in Sera of Patients with Neoplastic Disease by Schultz-Dale Test [PDF]
, 1958 J. G. Makari
openalex +1 more source
Advanced Science, EarlyView.This work unravels a novel function of CD103+ T cells in eradicating oxidative‐stressed somatic cells to prevent lung tumorigenesis and identifies specific CD103+ T cell‐decline as a key feature in the aged lung. This comprehensive study highlights the contribution of immuno‐dysregulation to the high incidence of aging‐associated lung cancers ...
Yu Xu +7 more
wiley +1 more source
The interrelationship of nitrogen and phosphorus in patients with certain neoplastic diseases [PDF]
, 1953 Leonard D. Fenninger +2 more
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The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression
Advanced Science, EarlyView.Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu +5 more
wiley +1 more source
The use of ultraviolet-microscopy, roentgen-rayabsorption, and radioautographic techniques in the study of neoplastic disease.A discussion of these cytophysical techniques [PDF]
, 1952 Patrick Fitzgerald, Arne Engström
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Mitigating Cell Cycle Effects in Multi‐Omics Data: Solutions and Analytical Frameworks
Advanced Science, EarlyView.The study highlights the cell‐cycle effects on multi‐omics analysis attributed to varying cell cycle compositions across cell types. To minimize the influence, we propose RTD correction in CNV calling with a high S‐phase ratio, and phase comparison in chromatin accessibility, DNA methylation, and transcriptomics.
Rui Nie +7 more
wiley +1 more source