Results 121 to 130 of about 1,996,477 (249)

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

Motor neuron disease can present as a paraneoplastic neurologic syndrome with various phenotypes. [PDF]

Brain Commun
Koropouli E, Bellos S, Aristeidou S, Daponte A, Gklinos P, Athanasopoulos F, Tsionis A, Andreadou E, Zouvelou V, Rentzos M.   +9 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Medical Management of Pigmented Villonodular Synovitis of the Right Ankle and Foot

Translation
Brianna Bailey, Divya Vijendra
doaj   +1 more source

Neoplastic Immune Mimicry Potentiates Breast Tumor Progression. [PDF]

Cancer Res
Berens EB, Khou S, Huang ET, Hoffman A, Johnson B, Kirchberger N, Sivagnanam S, Calistri NL, Derrick DS, Liby TA, McLean IC, Alanizi AA, Ozmen F, Ozmen TY, Mills GB, Hwang ES, Schedin P, Gonzalez H, Werb Z, Heiser LM, Coussens LM.   +20 more
europepmc   +1 more source

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi, Kentaro Miyake, Kota Sahara, Jun Yamamoto, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Ryusei Matsuyama, Itaru Endo   +9 more
wiley   +1 more source

Concurrent Development of B-Cell Lymphoblastic Lymphoma and Histiocytic Sarcoma in a C57BL/6 Laboratory Mouse: A Case Report. [PDF]

Vet Med Sci
Lee Y, Sung M, Sung SE, Kang KK, Seo MG, Hong IH, Lee S.   +6 more
europepmc   +1 more source

Proposal of Early Drain Exchange After Pancreatoduodenectomy From the View of Reducing Postoperative Pancreatic Fistula

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background To mitigate the progression of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD), appropriate drain management is required, and exchanging drainage tubes is commonly performed. However, the optimal timing of the first drain exchange has not yet been determined.
Taihei Soma, Mihoko Yamada, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Yoshiyasu Kato, Teiichi Sugiura, Katsuhiko Uesaka   +7 more
wiley   +1 more source

Stepwise management of adult intussusception caused by an appendiceal mucocele: a case report of endoscopic reduction followed by interval laparoscopic resection. [PDF]

J Surg Case Rep
Saito Y, Sato S.
europepmc   +1 more source

Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low‐Grade Malignant Tumors: A Comparative Analysis Based on 75‐g Oral Glucose Tolerance Test

Annals of Gastroenterological Surgery, EarlyView.
Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee, Keiko Kamei, Chihoko Nobori, Yuta Yoshida, Takaaki Murase, Atsushi Takebe, Yuki Okuda, Naru Babaya, Yoshihisa Hiromine, Ippei Matsumoto   +9 more
wiley   +1 more source