Results 121 to 130 of about 533,074 (342)

Supplementary Figure 1 from Stepwise Neoplastic Transformation of a Telomerase Immortalized Fibroblast Cell Line

, 2023
Samantha Zongaro, Elisa de Stanchina, Tina Colombo, Maurizio D’Incalci, Elena Giulotto, Chiara Mondello   +5 more
openalex   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, EarlyView.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage‐independent and cause tumors in newborn hamsters [PDF]

, 2002
Masayuki Takahashi, J. Carl Barrett, Takeki Tsutsui   +2 more
openalex   +1 more source

Supplementary Data from Polycomb Group Protein Enhancer of Zeste 2 Is an Oncogene That Promotes the Neoplastic Transformation of a Benign Prostatic Epithelial Cell Line [PDF]

, 2023
Breanne D.W. Karanikolas, Marxa L. Figueiredo, Lily Wu   +2 more
openalex   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Elevated Levels of Thymidylate Synthase Linked to Neoplastic Transformation of Mammalian Cells [PDF]

, 2004
Donna Voeller, Lambratu Rahman, Maria Zajac‐Kaye   +2 more
openalex   +1 more source

Data from Cell Division Cycle 25B Phosphatase Is Essential for Benzo(<i>a</i>)Pyrene-7,8-Diol-9,10-Epoxide–Induced Neoplastic Transformation

, 2023
Sanjay K. Srivastava, Pallavi Bansal, Tetsuya Oguri, John S. Lazo, Shivendra V. Singh   +4 more
openalex   +1 more source

Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation.

Carcinogenesis, 2014
Cheol-Jung Lee, Hye Suk Lee, H. Ryu, Mee-Hyun Lee, J. Lee, Yan Li, Z. Dong, Hyeong-Kyu Lee, Sei-Ryang Oh, Yong-Yeon Cho   +9 more
semanticscholar   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source