Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation [PDF]
Carcinogenesis, 2015 Cheol-Jung Lee +11 more
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The Autoimmune Gastritis Puzzle: Emerging Cellular Crosstalk and Molecular Pathways Driving Parietal Cell Loss and ECL Cell Hyperplasia [PDF]
CellsAutoimmune gastritis (AIG) is a chronic, organ-specific autoimmune disease characterized by progressive destruction of gastric parietal cells driven by autoreactive CD4+ T-cells, epithelial stress pathways, and microbial factors.
Sara Massironi +4 more
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eLife, 2021 Gene knockout of the master regulator of mitochondrial fission, Drp1, prevents neoplastic transformation. Also, mitochondrial fission and its opposing process of mitochondrial fusion are emerging as crucial regulators of stemness.
Brian Spurlock +9 more
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Effects of Curcumin on Sodium Arsenite Induced Neoplastic Cell Transformation in Balb/c 3T3 Cells [PDF]
Brazilian Archives of Biology and Technology, 2021 HIGHLIGHTS Sodium arsenite can cause neoplastic transformation in cells. Curcumin reduced cell viability and increased LDH activity in transformed Balb/c 3T3 cells. Curcumin caused DNA damage in transformed Balb/c 3T3 cells.
Busra Demircioglu +4 more
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Cumhuriyet Dental Journal, 2021 Objective. To assess the clinical-pathological factors related to the malignant transformation of oral leukoplakia. Materials and Methods. A search for articles on malignant transformation factors related to oral leukoplakia was conducted in the ...
Cristina Fuentes-perez +1 more
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Elastic Moduli of Cells undergoing Neoplastic Transformation [PDF]
Biophysical Journal, 2013 Using an Atomic Force Microscope (AFM) with a 5.3 um diameter spherical probe we determined the elastic modulus of human mammary epithelial cells (HMEC) as they undergo neoplastic transformation from normal to immortal, tumorigenic, and finally metastatic. We did the measurements over both cytoplasmic and nuclear regions; and as a function of the cells
Guo, Xinyi +2 more
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Clinicopathologic characteristics of ovarian clear cell carcinoma in the background of endometrioma: a surveillance strategy for an early detection of malignant transformation in patients with asymptomatic endometrioma [PDF]
Obstetrics & Gynecology Science, 2019 ObjectiveThis study aimed to analyze the clinical features of clear cell carcinoma in relation to endometriosis and to determine an appropriate surveillance strategy for the early detection of malignant transformation of endometrioma in asymptomatic ...
Joo-Hyuk Son +6 more
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Alternative Splicing and Its Impact as a Cancer Diagnostic Marker [PDF]
Genomics & Informatics, 2012 Most genes are processed by alternative splicing for gene expression, resulting in the complexity of the transcriptome in eukaryotes. It allows a limited number of genes to encode various proteins with intricate functions.
Yun-Ji Kim, Heui-Soo Kim
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Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation. [PDF]
PLoS ONE, 2015 Comprehensive analysis of alterations in gene expression along with neoplastic transformation in human cells provides valuable information about the molecular mechanisms underlying transformation.
Masao Takeuchi +13 more
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"Transformation of chronic myelogenous leukemia to Multiple Myeloma: A case report " [PDF]
Acta Medica Iranica, 2003 Chronic myelogenous leukemia (CML) is a stem cell disorder sometimes associated with lymphoproliferative disorders. CML may precede a lymphoproliferative disorder.
"Ghavamzadeh A +5 more
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