Results 271 to 280 of about 533,074 (342)

Neoplastic Cell Transformation by Heavy Charged Particles

Radiation Research Supplement, 1985
With confluent cultures of the C3H10T1/2 mammalian cell line, we have investigated the effects of heavy-ion radiation on neoplastic cell transformation. Our quantitative data obtained with high-energy carbon, neon, silicon, argon, iron, and uranium particles show that RBE is both dose- and LET-dependent for malignant cell transformation.
T C, Yang, L M, Craise, M T, Mei, C A, Tobias   +3 more
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Neoplastic Cell Transformation by Heavy Ions

Radiation Research, 1989
We have studied the induction of morphological transformation by heavy ions. Golden hamster embryo cells were irradiated with 95 MeV 14N ions (530 keV/microns), 22 MeV 4He ions (36 keV/microns), and 22 MeV 4He ions with a 100-microns Al absorber (77 keV/microns) which were generated by a cyclotron at the Institute of Physical and Chemical Research in ...
M, Suzuki, M, Watanabe, K, Suzuki, K, Nakano, I, Kaneko   +4 more
openaire   +3 more sources

Neoplastic cell transformation by high-LET radiation: Molecular mechanisms

Advances in Space Research, 1989
Experimental data on molecular mechanisms are essential for understanding the bioeffects of radiation and for developing biophysical models, which can help in determining the shape of dose-response curves at very low doses, e.g., doses less than 1 cGy. Although it has been shown that ionizing radiation can cause neoplastic cell transformation directly,
T C, Yang, L M, Craise, M T, Mei, C A, Tobias   +3 more
openaire   +3 more sources

Carcinogen-induced Cellular Thesaurismoses and Neoplastic Cell Transformation

1973
It has been known for a long time from human pathology that many tumors contain cells which store polysaccharides or lipids. So far such pathological storage phenomena have been interpreted as a consequence of the neoplastic cell transformation and to be related to the general disturbance of tumor cell metabolism.
P. Bannasch
openaire   +2 more sources

Sequential changes during neoplastic cell transformation

European Journal of Cancer and Clinical Oncology, 1985
M. Roberfroid
openaire   +2 more sources

Modeling Radiation-Induced Neoplastic Cell Transformation In Vitro and Tumor Induction In Vivo with the Local Effect Model

Radiation Research, 2021
Ionizing radiation induces DNA damage to cycling cells which, if left unrepaired or misrepaired, can cause cell inactivation or heritable, viable mutations.
A. Hufnagl, M. Scholz, T. Friedrich
semanticscholar   +1 more source

Cell surface protein and neoplastic transformation

Trends in Biochemical Sciences, 1976
A major fibroblast glycoprotein that is diminished after malignant transformation has been isolated and partially characterized. Reconstitution experiments indicate that the glycoprotein helps maintain normal cell shape, adhesion, and contact inhibition of movement.
Kenneth M. Yamada, Ira Pastan
openaire   +2 more sources

The Neoplastic Transformation of SCID Cells by Radiation

Radiation Research, 1999
Severe combined immunodeficiency (SCID) cells are hypersensitive to killing by ionizing radiation because of deregulation of DNA-dependent protein kinase (DNA-PK) and a concomitant deficiency in the repair of DNA double-strand breaks. The effect of this condition on the neoplastic transformation of SCID fibroblasts, designated SCID 3T1, has been ...
M, Lun, R L, Wells, S, Lang, N, Chawapun, M M, Elkind   +4 more
openaire   +2 more sources