Results 281 to 290 of about 533,074 (342)

Neoplastic transformation of primary tracheal epithelial cell cultures

Carcinogenesis, 1983
Primary cultures of rat tracheal epithelial cells were treated with the chemical carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) to quantitatively study the early events during neoplastic transformation. Epithelial cells were dissociated from tracheas of specific-pathogen-free Fischer-344 rats and were plated on collagen-coated tissue culture ...
S B, Pai, V E, Steele, P, Nettesheim
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Quantitative Neoplastic Transformation in C3H/10T1/2 Cells

1985
The development of mammalian cell culture systems in which neoplastic transformation can be induced by exposure to chemical and physical carcinogens provided a major stimulus to the study of carcinogenic mechanisms. Furthermore, the potential ability to quantitate the induction of neoplasia on a per cell basis has allowed the study of factors ...
J S, Bertram, J E, Martner
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Epigenetic Transformation by RNA from Human Neoplastic Cells

Oncology, 1973
The study of biologic properties of nucleic acids from either normal or malignant cells transcends the search for subviral infectivity. The differing results obtained in studying the behavior of nucleic acids from human malignant cells on primary cultures are critically reviewed in the light of the methodology involved.
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Transforming growth factors and control of neoplastic cell growth

Journal of Cellular Biochemistry, 1987
AbstractTransforming growth factors (TGFs) are peptides that affect the growth and phenotypic of cultured cells and bring about in nonmalignant fibroblastic cells phenotypic properties that resemble those of malignant cells. Two types of TGFs have been well characterized.
J, Keski-Oja, E B, Leof, R M, Lyons, R J, Coffey, H L, Moses   +4 more
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Cell Surfaces in Neoplastic Transformation

1971
Publisher Summary This chapter describes the properties, and the chemical and physiological aspects of cell surfaces in neoplastic transformation. Immunological surface disparities between normal and tumor cells have been studied for decades, while attempts to bring them into the realm of biochemistry have been extremely rare.
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Neoplastic transformation of rabbit cells by murine sarcoma viruses

International Journal of Cancer, 1982
AbstractNeoplastic transformation of rabbit cells by Kirsten murine sarcoma virus (Ki‐MSV), the Ki‐MSV pseudotype of baboon endogenous virus (Ki‐MSV[BaEV]) and the Moloney‐MSV pseudotype of feline leukemia virus (M‐MSV[FeLV]) is reported. Rabbit cells can be readily transformed by Ki‐MSV, Ki‐MSV(BaEV) and M‐MSV(FeLV). Rabbit cells transformed by Ki‐MSV
Rhim, J S, Bedigian, H G, Fox, R R
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Cadmium-induced neoplastic transformation of human prostate epithelial cells

International Journal of Oncology, 2002
Cadmium is a ubiquitous environmental human carcinogen. Epidemiological and animal studies have suggested its carcinogenic potential on the prostate. In the present study, non-tumorigenic human prostate epithelial cells (pRNS-1-1) immortalized by simian papovavirus (SV40) were transformed after repeated exposures to cadmium.
Keiichiro, Nakamura, Yutaka, Yasunaga, Daejin, Ko, Linda L, Xu, Judd W, Moul, Donna M, Peehl, Shiv, Srivastava, Johng S, Rhim   +7 more
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Neoplastic transformation of hamster embryo cells by heavy ions

Advances in Space Research, 1998
We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/micrometer. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to ...
Z, Han, H, Suzuki, F, Suzuki, M, Suzuki, Y, Furusawa, T, Kato, M, Ikenaga   +6 more
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Some Characteristics of Neoplastic Cell Transformation in Transgenic Mice

1996
The role of the expression of different cellular genes and viral oncogenes in malignant cell transformation is discussed. We pay special attention to the role of the genes for growth factors and their receptors and homeobox genes in oncogenesis. Based on both the literature and our own data, specific features of tumors developed in transgenic mice are ...
I N, Shvemberger, A N, Ermilov
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PD-1 Expression in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Large B-cell Richter Transformation (DLBCL-RT): A Characteristic Feature of DLBCL-RT and Potential Surrogate Marker for Clonal Relatedness

American Journal of Surgical Pathology, 2018
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a low-grade B-cell neoplasm and ∼2% to 9% patients develop an aggressive lymphoma, most commonly diffuse large B-cell lymphoma (Richter transformation, DLBCL-RT). Programmed death-1 (PD-
R. He, W. Ding, D. Viswanatha, Dong Chen, M. Shi, D. V. Van Dyke, Shulan Tian, L. Dao, S. Parikh, T. Shanafelt, T. Call, S. Ansell, J. Leis, M. Mai, C. Hanson, K. Rech   +15 more
semanticscholar   +1 more source