Results 291 to 300 of about 533,074 (342)

Neoplastic Transformation of Rat Embryo Cells by Simian Papovavirus SV40

Nature, 1967
SV40 virus manifests its oncogenic action only in hamsters1 and in mastomys2. There are, however, reports of its transformation in vitro of cells of hamsters3, mice4, rabbits4, pigs4, cows5, monkeys6 and humans7. The purpose of our investigation was to determine whether the SV40 virus possesses the ability to transform rat cells in vitro.
A D, Altstein, N N, Vassiljeva, O F, Sarycheva   +2 more
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Cell Growth, Tissue Neogenesis, and Neoplastic Transformation

1984
Exponential growth is rarely observed in vivo. most mammalian tissues, whether normal or malignant, exhibit nonexponential kinetics in which growth decelerates continuously with time (1–10). This deceleration is characterized by a gradual but progressive increase in a tissue’s doubling time, and a corresponding decline in its specific growth rate.
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In Which Cells Does Neoplastic Transformation Occur in Myelomatosis?

1992
Myelomatosis is strictly a neoplasm of plasma cells in bone marrow. It does not involve other sites of antibody production; thus, even when the monoclonal protein produced by the neoplastic clone is IgA1 or IgA2 the neoplastic cells are not found in the lamina propria of the gut (Leonard et al 1979).
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Neoplastic transformation of human epithelial cells in vitro.

Anticancer research, 1990
Efforts to investigate the progression of events that lead human cells of epithelial origin to become neoplastic in response to carcinogenic agents have been aided by the development of tissue culture systems for propagation of epithelial cells. We have recently developed an in vitro multistep model suitable for the study of human epithelial cell ...
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Neoplastic transformation of human cells in vitro.

Critical reviews in oncogenesis, 1993
Efforts to investigate the progression of events that lead normal human cells in culture to become neoplastic in response to carcinogenic agents have been aided by the development of the suitable in vitro model systems. For initial human cell transformation studies, a flat, nontumorigenic clonal line, originally derived from a human osteosarcoma (HOS),
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Positive Mediators of Cell Proliferation in Neoplastic Transformation

2002
Cancer is not a single disease, but a collection of diseases all of which are related by a common root cause: the loss of controlled cell growth. Cancer begins as a clonal disease, that is, it stems from the genetic corruption of a single cell. This conversion of a normal cell into the neoplastic state is a multi-step phenomenon called neoplastic ...
James N. Welch, Susan A. Chrysogelos
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Heterochromatin, Satellite DNA, and Transformed Neoplastic Cells

JNCI: Journal of the National Cancer Institute, 1972
N C, Popescu, J A, DiPaolo
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Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions

Ca-A Cancer Journal for Clinicians, 2023
Balazs Dome
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023

exaly  

Radiation-Induced Neoplastic Transformation of Human Cell Hybrids

1987
In vitro cell systems are well established in the study of mechanisms of neoplastic transformation by a variety of agents including chemicals, ultraviolet light and ionizing radiation (for recent reviews see references 1-4). However, with few exceptions, systems that are used for quantitative studies are rodent-derived cell lines, usually of ...
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