Results 61 to 70 of about 508,130 (309)

Reduction of T Lymphoma Cells and Immunological Invigoration in a Patient Concurrently Affected by Melanoma and Sezary Syndrome Treated With Nivolumab

Frontiers in Immunology, 2020
Despite the recent availability of several new drugs in hemato-oncology, T-cell lymphomas are still incurable and PD-1 blockade could represent a therapeutic chance for selected patients affected by these malignancies, although further studies are ...
Maria Grazia Narducci, Anna Tosi, Alessandra Frezzolini, Enrico Scala, Francesca Passarelli, Laura Bonmassar, Alessandro Monopoli, Maria Pina Accetturi, Maria Cantonetti, Gian Carlo Antonini Cappellini, Federica De Galitiis, Antonio Rosato, Antonio Rosato, Mario Picozza, Giandomenico Russo, Stefania D’Atri   +15 more
doaj   +1 more source

Gli1 mediates lung cancer cell proliferation and sonic hedgehog-dependent mesenchymal cell activation. [PDF]

, 2013
Non-Small-Cell-Lung-Cancer (NSCLC) represents approximately 85% of all lung cancers and remains poorly understood. While signaling pathways operative during organ development, including Sonic Hedgehog (Shh) and associated Gli transcription factors (Gli1 ...
Hennen, Elisabeth, Olga Bermudez, Oliver Eickelberg, Olga Bermudez (410727), Ina Koch (7903), Oliver Eickelberg (153848), Eickelberg, O., Bermudez, O., Koch, I., Lindner, Michael, Elisabeth Hennen, Hennen, E., Koch, Ina, Elisabeth Hennen (410728), Bermudez, Olga, Michael Lindner, Ina Koch, Michael Lindner (383308), Lindner, M., Eickelberg, Oliver   +19 more
core   +1 more source

Tumor-Infiltrating Macrophages in Post-Transplant, Relapsed Classical Hodgkin Lymphoma Are Donor-Derived. [PDF]

PLoS ONE, 2016
Tumor-associated inflammatory cells in classical Hodgkin lymphoma (CHL) typically outnumber the neoplastic Hodgkin/Reed-Sternberg (H/RS) cells. The composition of the inflammatory infiltrate, particularly the fraction of macrophages, has been associated ...
Genevieve M Crane, Mark A Samols, Laura A Morsberger, Raluca Yonescu, Michele L Thiess, Denise A S Batista, Yi Ning, Kathleen H Burns, Milena Vuica-Ross, Michael J Borowitz, Christopher D Gocke, Richard F Ambinder, Amy S Duffield   +12 more
doaj   +1 more source

Circulating Tumor DNA as a Tool of Surveillance and Early Indicator of Relapse in Sarcoma Patients

International Journal of Medical Students
Background: The use of circulating tumor DNA (ctDNA) has been increasingly explored to monitor treatment response and recurrence surveillance in sarcoma patients. Given the minimally invasive method of measurement via blood samples, and its accuracy and
Esha Sankhala, Earl Brien, Jaya Gill, Leo Mascarenhas   +3 more
doaj   +1 more source

Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers

Cells, 2019
As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders.
Valentina Karin-Kujundzic, Ida Marija Sola, Nina Predavec, Anamarija Potkonjak, Ema Somen, Pavao Mioc, Alan Serman, Semir Vranic, Ljiljana Serman   +8 more
doaj   +1 more source

The Overview of Perspectives of Clinical Application of Liquid Biopsy in Non-Small-Cell Lung Cancer

Life, 2022
The standard diagnostics procedure for non-small-cell lung cancer (NSCLC) requires a pathological evaluation of tissue samples obtained by surgery or biopsy, which are considered invasive sampling procedures.
Aleksandra Bożyk, Marcin Nicoś
doaj   +1 more source

The use of RT-nested PCR of prostate specific antigen to detect hematogenous neoplastic cells in patiens with prostate adenocarcinoma

, 1997
The aim of this study was to determine the presence of hematogenous neoplastic cells in patients with prostate cancer. We used a reverse transcription (RT) 'nested' polymerase chain reaction (PCR) of prostate-specific antigen (PSA) mRNA to detect the ...
GUAZZELLI R., PONCHIETTI, ROBERTO, DI LORO F., PIAZZINI M., FATINI C., SARDI I.   +5 more
core   +1 more source

Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

Science Advances, 2018
Peripheral blood MФ–cancer cell fusion hybrids identified in cancer patients correlate with disease stage and overall survival. High lethality rates associated with metastatic cancer highlight an urgent medical need for improved understanding of biologic
C. Gast, Alain D. Silk, L. Zarour, L. Riegler, Joshua G. Burkhart, Kyle T. Gustafson, M. Parappilly, Minna Roh-Johnson, James R Goodman, Brennan Olson, Mark Schmidt, John R. Swain, Paige S. Davies, V. Shasthri, S. Iizuka, Patrick Flynn, S. Watson, J. Korkola, S. Courtneidge, Jared M. Fischer, J. Jaboin, K. Billingsley, C. Lopez, J. Burchard, J. Gray, L. Coussens, B. Sheppard, M. Wong   +27 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Circulating cell-free DNA as a biomarker in the diagnosis and prognosis of colorectal cancer

Brazilian Journal of Pharmaceutical Sciences, 2018
Colorectal cancer (CRC) is a disease without evident clinical symptoms in early stages, leading to late diagnosis and disease management. Current diagnostic and prognostic tools require invasive procedures and circulating molecular biomarkers fail to ...
Isadora Bernardo David de Oliveira, Rosario Dominguez Crespo Hirata   +1 more
doaj   +1 more source