Results 151 to 160 of about 432,951 (336)

The E. Donnall Thomas Lecture: Normal and Neoplastic Stem Cells

Biology of Blood and Marrow Transplantation, 2008
AbstractDr. Irving Weissman was the honored E. Donnall Thomas lecturer at the Tandem BMT Meetings, held on February 10, 2007, at Keystone, Colorado. Dr. Weissman has been a major player, and has provided us with enormous insight into many areas of biology, dating back to his high school days in Montana.
openaire   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

Epilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou   +27 more
wiley   +1 more source

Effect of Fruit Maturation Stage on the Chemical Composition and Antioxidant and Cytotoxic Activities of Piper nigrum Essential Oil

Flavour and Fragrance Journal, EarlyView.
The essential oils of Piper nigrum show marked chemical and biological variation across fruit maturation stages. Ripe fruits yield oils with the strongest antioxidant and cytotoxic activities, demonstrating that maturation directly modulates volatile composition and enhances the bioactive potential of this aromatic species.
Marcio Marcelo da Siva Pessoa, Jorddy Neves Cruz, Ingryd Nayara de Farias Ramos, André Salim Khayat, Eloisa Helena de Aguiar Andrade, José de Arimatéia Rodrigues do Rego, Davi do Socorro Barros Brasil   +6 more
wiley   +1 more source

Immunotherapy targeting glioma stem cells and its microenvironment

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Glioma is the most prevailing primary malignant tumor in the central nervous system.Given that glioma stem cells (GSCs) and its microenvironment are pivotal for the occurrence and progressionof glioma, various targeted therapy including immunotherapy is ...
Hai⁃yang WANG, Jun DONG
doaj  

Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon [PDF]

, 2014
Ann‐Marie Baker, Biancastella Cereser, Samuel Melton, Alexander G. Fletcher, Manuel Rodriguez‐Justo, Paul Tadrous, Adam Humphries, George Elia, Stuart A.C. McDonald, Nicholas A. Wright, Benjamin D. Simons, Marnix Jansen, Trevor A. Graham   +12 more
openalex   +1 more source

Supplementary Figure S1 from eIF4E Threshold Levels Differ in Governing Normal and Neoplastic Expansion of Mammary Stem and Luminal Progenitor Cells

, 2023
Svetlana Avdulov, Jeremy Herrera, Karen Smith, Mark A. Peterson, José R. Gómez-García, Thomas C. Beadnell, Kathryn L. Schwertfeger, Alexey O. Benyumov, J. Carlos Manivel, Shunan Li, Anja‐Katrin Bielinsky, Douglas Yee, Peter B. Bitterman, Vitaly A. Polunovsky   +13 more
openalex   +1 more source

Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices [PDF]

, 2015
Journal of Osseointegration Volume 7, Issue 1, 1 March 2015, Pages 2-7 Open Access Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices (Article) Pozzuoli, A.a, Gardin, C.b, Aldegheri, R.a, Bressan, E.c,
Aldegheri, R., Arrigoni, P., Biz, Carlo, Bressan, Eriberto, Calvo Guirado, J. L., Feroni, L., Gardin, Chiara, Isola, Maurizio, Pozzuoli, Assunta, Zavan, Barbara   +9 more
core   +1 more source

In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation [PDF]

, 2011
Tamra E. Werbowetski‐Ogilvie, Ludivine Coudière Morrison, Aline Fiebig‐Comyn, Mickie Bhatia   +3 more
openalex   +1 more source

Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon [PDF]

, 2019
Ann‐Marie Baker, Biancastella Cereser, Samuel Melton, Alexander G. Fletcher, Manuel Rodriguez‐Justo, Paul Tadrous, Adam Humphries, George Elia, Stuart A.C. McDonald, Nicholas A. Wright, Benjamin D. Simons, Marnix Jansen, Trevor A. Graham   +12 more
openalex   +1 more source