Results 141 to 150 of about 438,052 (300)

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte‐mediated etiology of epileptic cortical thinning

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang   +9 more
wiley   +1 more source

Spontaneous regression of equine sarcoids is an exceptional event

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source

Effect of Fruit Maturation Stage on the Chemical Composition and Antioxidant and Cytotoxic Activities of Piper nigrum Essential Oil

open access: yesFlavour and Fragrance Journal, EarlyView.
The essential oils of Piper nigrum show marked chemical and biological variation across fruit maturation stages. Ripe fruits yield oils with the strongest antioxidant and cytotoxic activities, demonstrating that maturation directly modulates volatile composition and enhances the bioactive potential of this aromatic species.
Marcio Marcelo da Siva Pessoa   +6 more
wiley   +1 more source

A Rare Giant Pleural Thymoma in Posterior Mediastinum. [PDF]

open access: yes, 2012
Thymoma is an epithelial neoplasm of the thymus, which commonly lies in the anterior mediastinum. Unusually, thymomas can also be found in other locations. Surgical excision, when feasible, appears to provide good results. We encountered a rare case of a
Kalloli, M   +3 more
core  

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Association of Chronic Diseases With Herpes Zoster in China: A Nationwide Population‐Based Survey

open access: yesHealth Care Science, EarlyView.
Chronic disease was associated with elevated herpes zoster risk (aOR = 1.84, 95% CI: 1.51–2.24). Among 14 chronic conditions, heart disease showed the strongest association (aOR = 2.91, 95% CI: 2.07–4.10), followed by diabetes (aOR = 2.04, 95% CI: 1.48–2.80) and hypertension (aOR = 1.89, 95% CI: 1.47–2.42).
Wenhui Zhu   +10 more
wiley   +1 more source

Immunotherapy targeting glioma stem cells and its microenvironment

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Glioma is the most prevailing primary malignant tumor in the central nervous system.Given that glioma stem cells (GSCs) and its microenvironment are pivotal for the occurrence and progressionof glioma, various targeted therapy including immunotherapy is ...
Hai⁃yang WANG, Jun DONG
doaj  

Identification Of Mitotically Competent SOX2+ Cells In White Matter Of Normal Human Adult Brain [PDF]

open access: yes, 2011
SOX2 expression is linked to the undifferentiated state of stem cells in mammalian neurogenic niches. While its expression has been reported in the adult human subventricular zone (SVZ), to date it has not been detected in adult human white matter.
Angel Ayuso-Sacido   +5 more
core   +1 more source

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