Results 151 to 160 of about 438,052 (300)

OCT-4 Is a Good Predictive Biomarker for Local Recurrence in Head and Neck Basal Cell Carcinoma

open access: yesJournal of Islamic Dental Association of Iran, 2017
Background and Aim: Basal cell carcinoma (BCC) is considered to be the most common malignancy in humans and occurs primarily in the skin especially in the head and neck region.
Fereshteh Baghai Naini   +3 more
doaj  

Cytokine secretion in stem cells of cattle infected with bovine leukaemia virus

open access: yesJournal of Veterinary Research
Bovine leukaemia virus (BLV) is a Deltaretrovirus responsible for enzootic bovine leukosis, the most common neoplastic disease of cattle. It deregulates the immune system, favouring secondary infections and changes in the blood and lymphatic tissues ...
Szczotka Maria, Kuźmak Jacek
doaj   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

open access: yesInternational Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim   +22 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

Deep learning‐based prediction of cervical lymph node metastasis and genetic alterations from whole‐slide images of thyroid cancer frozen sections

open access: yesInterdisciplinary Medicine, EarlyView.
Deep learning models accurately predict cervical lymph node metastasis and key genetic mutations (BRAF/TERT) directly from thyroid cancer frozen sections. This AI‐driven pipeline provides a rapid real‐time tool to guide intraoperative surgical decisions, helping to optimize surgical extent and prevent both over‐ and under‐treatment without the need for
Mingxing Qiu   +20 more
wiley   +1 more source

Establishment of 9L/F344 rat intracerebral glioma model of brain tumor stem cells

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To establish the 9L/F344 rat intracerebral glioma model of brain tumor stem cells.  Methods Rat 9L gliosarcoma stem-like cells were cultured in serum-free suspension. The expression of CD133 and nestin were tested by immunohistochemistry.
Zong-yu XIAO   +2 more
doaj  

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