Results 181 to 190 of about 389,847 (293)

Investigation of hallmark epigenetic changes in a cancer stem cell model

, 2010
Epigenetic control of gene expression is vital for normal development and differentiation of cells, and is also important in the development of disease.
Wild, L.
core  

Identification of tumor initiating cells and early marker genes in histologically normal colonic mucosa that lead to neoplastic transformation. [PDF]

Neoplasia
Jaiswal S, The S, Chang TS, Shi J, Wang TD.   +4 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Identification of CD74-positive antigen presenting glioma cells in primary human tumors and murine models of NF1 high-grade glioma. [PDF]

Mol Cancer Ther
Brosius SN, Sussman JH, DiStefano IA, Grothusen GP, Natan KN, Seka I, Foltz S, Labella K, Bosse KR, Tan K, De Raedt T.   +10 more
europepmc   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, EarlyView.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Universality of a mesenchymal transition signature in invasive solid cancers

, 2012
In this brief communication, additional computational validation is provided consistent with the unifying hypothesis that a shared biological mechanism of mesenchymal transition, reflected by a precise gene expression signature, may be present in all ...
Dimitris Anastassiou
core  

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133⁺ ovarian cancer stem cells. [PDF]

Oncol Rep
Long Q, Yang R, Lu W, Zhu W, Zhou J, Zheng C, Zhou D, Yu L, Wu J.   +8 more
europepmc   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Recombinant human erythropoietin therapy in patients with cancer: efficacy, risks and the controversy of EpoR expression. [PDF]

Drugs Context
Sturiale A, Sessa C, Martina R, Maltese S, Campo S, Crascì E, Galeano D, Alessandrello I, Zuppardo C, Scollo V, Zirino F, Distefano G, Tigano A, Giglio E, Ficara V, Messina RM, Musumeci MS, Cicero E, Dimartino L, Rauseo F, Morale W.   +20 more
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source