Results 201 to 210 of about 438,052 (300)

Human organoid tumor transplantation identifies functional glioblastoma-microenvironment communication mediated by PTPRZ1. [PDF]

open access: yesCell Rep
Ge W   +15 more
europepmc   +1 more source

Decoding Leukemic Stem Cells in AML: From Identification to Targeted Eradication. [PDF]

open access: yesDiseases
Apostolidou E   +5 more
europepmc   +1 more source

Exploiting ALK inhibition in anaplastic large cell lymphoma: Biological rationale and therapeutic integration

open access: yesBritish Journal of Haematology, EarlyView.
Summary Mature T‐cell lymphomas comprise a heterogeneous group of aggressive non‐Hodgkin lymphomas with limited therapeutic options in the relapsed or refractory setting. Among them, anaplastic lymphoma kinase (ALK)‐positive anaplastic large cell lymphoma (ALCL) represents a biologically distinct subtype driven by constitutive activation of ALK fusion ...
Santino Caserta   +13 more
wiley   +1 more source

Improved survival with fludarabine‐based therapies in mixed phenotype acute leukaemia: A population‐based study using the WHO 2022 classification

open access: yesBritish Journal of Haematology, EarlyView.
Summary Mixed phenotype acute leukaemia (MPAL) is a rare subtype of acute leukaemia possessing significant therapeutic challenges, as no standardized, evidence‐based treatment regimen has been defined. In this nationwide study, we aimed to assess the effect of an acute lymphoid leukaemia (ALL)‐like regimen; an acute myeloid leukaemia (AML)‐like regimen;
Lisa‐Maj Christensen   +11 more
wiley   +1 more source

Systemic Mastocytosis, KIT and the Effects of KIT Tyrosine Kinase Inhibitors on Mast Cell and Basophil Activation. [PDF]

open access: yesCurr Allergy Asthma Rep
Valent P   +15 more
europepmc   +1 more source

High frequency of CD95+/CD45RA− regulatory T cells defines an immunosuppressive profile associated with MDS progression

open access: yesBritish Journal of Haematology, EarlyView.
Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Romain Vazquez   +18 more
wiley   +1 more source

Early cellular plasticity promotes progression and dissemination in pancreatic adenocarcinoma. [PDF]

open access: yesCancer Metastasis Rev
Innamorati G   +4 more
europepmc   +1 more source

Mast Cells in Acute COVID‐19 Patients

open access: yes
Allergy, EarlyView.
Ilan Zaffran   +8 more
wiley   +1 more source

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