Results 221 to 230 of about 438,052 (300)

An Immune Dysfunction Signature Score Predicts Survival in MDS Patients: Insights From a Longitudinal, Multicenter Study

Cancer Science, EarlyView.
An immune dysfunction score (IDS) provides independent prognostic information in MDS and CMML, complements current risk models, mirrors disease changes, and reflects underlying immune impairment. IDS may also highlight therapeutic sensitivities, supporting its use as a practical biomarker for risk stratification and clinical follow‐up.
Yu‐Hung Wang, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Luca Guarnera, Wan‐Hsuan Lee, Chi‐Yuan Yao, Andres Jerez, Kristian Gurashi, Kiran Batta, Hsin‐An Hou, Wen‐Chien Chou, Mrinal S. Patnaik, Jaroslaw Maciejewski, Daniel H. Wiseman, Chien‐Chin Lin, Hwei‐Fang Tien   +16 more
wiley   +1 more source

Epigenetic memory of colitis promotes tumour growth. [PDF]

Nature
Nagaraja S, Ojeda-Miron L, Zhang R, Oreskovic E, Hock C, Hu Y, Zeve D, Sharma K, Hyman RR, Zhang Q, Castillo A, Breault DT, Yilmaz ÖH, Buenrostro JD.   +13 more
europepmc   +1 more source

Limited diagnostic utility of bone marrow sampling in PET‐defined limited‐stage follicular lymphoma

British Journal of Haematology, EarlyView.
Marissa Solow, Carolyn Owen, Colin Stewart, Jeffrey Q. Cao, Alex Balogh, Sarah Perry, Mona Shafey, Lesley Street, Robert Puckrin   +8 more
wiley   +1 more source

Population‐Based Identification of Clonal Hematopoiesis Using Peripheral Blood Whole‐Genome Sequencing in Japan

Cancer Science, EarlyView.
Whole‐genome sequencing of ~50,000 individuals from the Tohoku Medical Megabank (TMM) cohort defines the prevalence, mutational landscape, and age dependency of clonal hematopoiesis in the Japanese population, demonstrating overall concordance with clonal hematopoiesis detected in cancer patients.
SungGi Chi, Ikuko N. Motoike, Takao Fujisawa, Yumi Yamaguchi‐Kabata, Takahiro Nobukuni, Kengo Kinoshita, Yoshiaki Nakamura, Hideaki Bando, Takayuki Yoshino, Kinuko Ohneda, Katsuya Tsuchihara, Yosuke Minami, Riu Yamashita   +12 more
wiley   +1 more source

Spatial Transcriptomics Meets Histochemistry: Insights from Glioblastoma as a Model System. [PDF]

Acta Histochem Cytochem
Tomioka S, Kitazawa R, Haraguchi R, Takaoka Y, Inoue A, Kitazawa S.   +5 more
europepmc   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, EarlyView.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

I. Enhanced Autologous Immune Enhancement Therapy (AIET) for Cancer Treatment in Vietnam: From Clinical Trials to Broader. [PDF]

J Stem Cells Regen Med
Liem NT.
europepmc   +1 more source

Comparative Analysis of Incidental and Non‐Incidental Papillary Thyroid Microcarcinoma Outcomes: Implications on Management Recommendations

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Papillary thyroid microcarcinomas (PTMC) are defined by the World Health Organisation (WHO) as tumours measuring ≤ 10 mm. Incidental PTMCs, or lesions discovered postoperatively on histological examination, are less extensively studied compared with lesions diagnosed preoperatively through cytology, particularly in terms of ...
Emma A. Finnegan, Justin M. Hintze, Anne McGowan, James Gibney, Conall W. R. Fitzgerald, John Kinsella, Marie Louise Healy   +6 more
wiley   +1 more source

Mixed gangliocytoma-pituitary neuroendocrine tumour: clinical, immunohistochemical, and molecular genetic profiles in a series of four patients. [PDF]

Acta Neuropathol Commun
Dalakas K, Engström BE, Tebani A, Bontell TO, Larsson A, Nord H, Lindskog C, Pontén F, Boldt HB, Ragnarsson O, Casar-Borota O.   +10 more
europepmc   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, EarlyView.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source