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Abstract SY08-02: Normal and neoplastic stem cells
Cancer Research, 2016Abstract The transition from single cell species to multicellular organisms led to organ and tissue development. The development and maintenance of organs/tissues in multicellular organisms has resulted in the emergence of specialized cells that self-renew as well as differentiate; these rare cells are stem cells.
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Characterization of human embryonic stem cells with features of neoplastic progression
Nature Biotechnology, 2009Cultured human embryonic stem (hES) cells can acquire genetic and epigenetic changes that make them vulnerable to transformation. As hES cells with cancer-cell characteristics share properties with normal hES cells, such as self-renewal, teratoma formation and the expression of pluripotency markers, they may be misconstrued as superior hES cells with ...
Werbowetski-Ogilvie, Tamara +15 more
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Cancer, Stem Cells and the Neoplastic Niche
2009Conventionally, cancer is treated as a homogenous mass of highly proliferative cells, with therapeutics designed to destroy rapidly dividing cells. However, not only are cancers heterogeneous, but also small subsets are endowed with the ability to initiate cancer formation and metastasis.
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Cancer Letters, 2012
Giant cell tumor (GCT) derived stromal cells (GCTSCs) have been identified as the neoplastic cell population of GCTs. Within these stromal cells a subpopulation has been identified that shares several features with mesenchymal stem cells (MSCs) indicating that these neoplastic cells develop from MSCs.
Joerg, Fellenberg +3 more
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Giant cell tumor (GCT) derived stromal cells (GCTSCs) have been identified as the neoplastic cell population of GCTs. Within these stromal cells a subpopulation has been identified that shares several features with mesenchymal stem cells (MSCs) indicating that these neoplastic cells develop from MSCs.
Joerg, Fellenberg +3 more
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Stem Cells, Nonproliferating Cells, and Their Kinetics in Normal and Neoplastic Tissues
1977At this time of increased efforts and promising results in the therapy of malignant neoplasias, it seems appropriate to review critically some principal aspects of Cell. and tissue kinetics as they relate to stem cells, to nonproliferating cells, and to Cell. recruitment into the mitotic cycle.
Milan Potmesil +2 more
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Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity
Nature Reviews Cancer, 2022Ryan N Gimple +2 more
exaly
[Stem cell assay of neoplastic cells].
Nihon rinsho. Japanese journal of clinical medicine, 1986H, Takahashi, N, Saijo
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Adult stem cells in regenerating and neoplastic colon tissue
Pathology - Research and Practice, 2004V. Weiler +4 more
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