Results 21 to 30 of about 119,164 (256)

Urological cancer related to familial syndromes

International Brazilian Journal of Urology
Cancer related to hereditary syndromes corresponds to approximately 5-10% of all tumors. Among those from the genitourinary system, many tumors had been identified to be related to genetic syndromes in the last years with the advent of new molecular ...
Walter Henriques da Costa, George Jabboure Netto, Isabela Werneck da Cunha   +2 more
doaj   +1 more source

Cancer Predisposition Syndromes and Medulloblastoma in the Molecular Era

Frontiers in Oncology, 2020
Medulloblastoma is the most common malignant brain tumor in children. In addition to sporadic cases, medulloblastoma may occur in association with cancer predisposition syndromes.
Roberto Carta, Giada Del Baldo, Evelina Miele, Agnese Po, Zein Mersini Besharat, Francesca Nazio, Giovanna Stefania Colafati, Eleonora Piccirilli, Emanuele Agolini, Martina Rinelli, Mariachiara Lodi, Antonella Cacchione, Andrea Carai, Luigi Boccuto, Luigi Boccuto, Elisabetta Ferretti, Franco Locatelli, Franco Locatelli, Angela Mastronuzzi   +18 more
doaj   +1 more source

Cutaneous paraneoplastic syndromes as early indicators of neoplastic diseases

Medycyna Paliatywna
Cutaneous paraneoplastic syndromes play an important role in the detection of malignant neoplasms and may represent the first clinical sign of an underlying malignancy. The skin is the second most frequently involved organ, after the endocrine system and
Julia Sawicka, Zuzanna Duczkowska, Agnieszka Zdanowska, Joanna Czuwara, Lidia Rudnicka, Tomasz Dzierżanowski   +5 more
doaj   +1 more source

A diagnostic approach to neurocutaneous syndromes

Arquivos de Neuro-Psiquiatria
Neurocutaneous syndromes are a group of genetically and phenotypically diverse disorders that primarily affect the skin, central and peripheral nervous systems, and eyes.
Sofia Mônaco Gama, João Vitor Gerdulli Tamanini, Marianna Pinheiro Moraes de Moraes, Thiago Yoshinaga Tonholo Silva, Fernanda Teresa de Lima, José Luiz Pedroso, Orlando Graziani Povoas Barsottini   +6 more
doaj   +1 more source

FROM FAMILIES SYNDROMES TO GENES… THE FIRST CLINICAL AND GENETIC CHARACTERIZATIONS OF HEREDITARY SYNDROMES PREDISPOSING TO CANCER: WHAT WAS THE BEGINNING?

Revista Médica Clínica Las Condes, 2017
Assessment for hereditary susceptibility to cancer is considered standard of care, as it impacts not only a clinician's understanding of cancer causation but also options for prevention and treatment.
Charité Ricker, MS, LCGC
doaj   +1 more source

Safety and efficacy of chemoprevention for familial adenomatous polyposis: a systematic review and meta-analysis [PDF]

Annals of Coloproctology
Purpose Familial adenomatous polyposis is a hereditary condition that predisposes individuals to colorectal cancer. This study aimed to evaluate the efficacy and safety of pharmacological therapies for reducing polyp number, burden, and size in ...
Francisco Tustumi, Amanda Park, Eric Toshiyuki Nakamura, Thaís Cabral de Melo Viana, Elis Nogara Lisboa, Rodrigo Moisés de Almeida Leite, Sergio Eduardo Alonso Araujo, Pedro Luiz Serrano Usón Jr, Kaique Flávio Xavier Cardoso Filardi   +8 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

The role of hereditary colorectal cancer registries in identification of high risk patients and treatment improvement

Alʹmanah Kliničeskoj Mediciny, 2018
Up to 10% of cases of sporadic colorectal cancer are considered to be related to hereditary genetic factors. The rates of colorectal cancer related to already identified genetic factors is about 5%.
D. Yu. Pikunov, M. Kh. Toboeva, A. S. Tsukanov   +2 more
doaj   +1 more source

Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

Frontiers in Oncology, 2021
The neurofibromatosis syndromes, including NF1, NF2, and schwannomatosis, are tumor suppressor syndromes characterized by multiple nervous system tumors, particularly Schwann cell neoplasms.
Anusha Amaravathi, Anusha Amaravathi, Janet L. Oblinger, D. Bradley Welling, A. Douglas Kinghorn, Long-Sheng Chang, Long-Sheng Chang, Long-Sheng Chang   +7 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source