Results 101 to 110 of about 22,017 (305)
Urinary Neopterin Concentrations in Healthy Individuals with Household Contact
Increased neopterin concentrations in serum and urine indicate activation of cell-mediated immunity. In this study, urinary neopterin concentrations of a family consisting of 1 child (aged 5 years), her parents, and her grandparents were determined over ...
Winkler Christiana +3 more
doaj +1 more source
Inflammation and immune activation play an important role in the pathogenesis of cardiac remodelling in patients with heart failure. The aim of this study was to assess whether biomarkers of inflammation and immune activation are linked to disease ...
L. Lanser +4 more
semanticscholar +1 more source
BackgroundEcological immunology proposes that the optimal immune defence, and the costs coming with it, vary across environments. In environments with higher pathogen load, the immune system should experience greater challenges and, therefore, investment
V. Behringer +6 more
semanticscholar +1 more source
A Systematic Review and Meta‐Analysis of the Role of Peripheral Inflammation in Delirium
This review found peripheral inflammation is associated with delirium. Preceding delirium, the neutrophil‐to‐lymphocyte ratio (NLR), interleukin‐6 (IL‐6), C‐reactive protein (CRP), and Leukocyte Count(WBC) were higher, and insulin‐like growth factor‐1 (IGF‐1) lower, in those that developed delirium.
Hannah C. Moorey +4 more
wiley +1 more source
Urinary Neopterin in Patients with Ovarian Cancer
Urinary neopterin, an indicator of systemic immune activation, is increased in most patients with epithelial ovarian carcinoma (EOC) and is an independent prognostic indicator.
Melichar Bohuslav +8 more
doaj +1 more source
Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice
Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121,
A. Licari +3 more
semanticscholar +1 more source
Pharmacodynamic (PD) biomarkers can support biosimilarity assessment, potentially reducing the need for comparative clinical efficacy studies. This study aimed to characterize previously identified proteomic PD biomarker candidates for Interferon beta‐1a (IFNβ‐1a, n = 248) and pegylated IFNβ‐1a (pegIFNβ‐1a, n = 528) biologics at therapeutic doses, to ...
Lakshmi Manasa S. Chekka +15 more
wiley +1 more source
Salivary neopterin concentrations in patients with cancer of the oral cavity
Tumors of the oral cavity are relatively common malignancies with a poor prognosis. Use of both prognostic and predictive biomarkers in saliva represents one approach to improve the management of patients with these cancers.
Pink Richard +5 more
doaj +1 more source
C-reactive protein, neopterin and lactoferrin are biomarkers of atherosclerotic disease. We aimed to assess changes in these biomarkers after conservative and surgical weight loss interventions in individuals with morbid obesity, to evaluate associations
M. Aasbrenn, P. Farup, V. Videm
semanticscholar +1 more source
Clinical Value of Neopterin In Infectious Complications
Neopterin, a pteridine intermediate metabolite in the biopterine synthetic pathway, is synthesized and secreted by monocyte/macrophages upon stimulation, mainly by gamma-interferon by activated T cells.
Iwagaki Hiromi +5 more
doaj +1 more source

