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A novel measure of antiretroviral activity in cerebrospinal fluid and association with HIV persistence and cognitive function. [PDF]
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Experimental Dermatology, 1999
Abstract: Neopterin was discovered in bee larvae, in worker bees and in royal jelly. The compound was termed “neopterin” to denote that it might start a new (Greek, neo) epoch in pteridine research. Increased concentrations of neopterin were reported in patients with viral infections, suggesting that increased neopterin may originate from the immune ...
exaly +3 more sources
Abstract: Neopterin was discovered in bee larvae, in worker bees and in royal jelly. The compound was termed “neopterin” to denote that it might start a new (Greek, neo) epoch in pteridine research. Increased concentrations of neopterin were reported in patients with viral infections, suggesting that increased neopterin may originate from the immune ...
exaly +3 more sources
Neopterin in Acute Pancreatitis
Scandinavian Journal of Gastroenterology, 1996Activation of the cellular immune system may play a role in the pathogenesis of acute pancreatitis (AP); it has recently been proposed that excessive leukocyte stimulation may lead to the most severe forms of AP. The aim of this study was to investigate serum neopterin, a useful in vivo marker of macrophage activation, in mild and severe AP and its ...
G, Uomo +6 more
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Diseases of the Colon & Rectum, 1987
Neopterin is compared with other tumor markers in colorectal carcinoma. Its sensitivity is clearly lower than that of CEA, TPA and CA 19/9 and is even lower than the sensitivity of the erythrocyte sedimentation rate. The ability of neopterin to discriminate between different tumor stages is also lower than that of the other markers.
H, Putzki +3 more
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Neopterin is compared with other tumor markers in colorectal carcinoma. Its sensitivity is clearly lower than that of CEA, TPA and CA 19/9 and is even lower than the sensitivity of the erythrocyte sedimentation rate. The ability of neopterin to discriminate between different tumor stages is also lower than that of the other markers.
H, Putzki +3 more
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Neopterin in clinical practice
Clinica Chimica Acta, 1991Neopterin and the closely related biopterin belong to a group of pteridine compounds containing a 2-amino, 4-0~0, pyrimidino-pyrazino-(pterin) ring, with a 3-carbon side-chain on carbon 6. Pteridines were first described as pigments of insects and lower vertebrates [ll. During the past ten years increased concentrations of neopterin in body fluids have
M M, Müller +3 more
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Determination of Neopterin as a Prognostic Indicator Using Neopterin-Imprinted Cryogel Membranes
2021Neopterin (Neo) is thought of as a key biomarker for the diagnosis and prognosis of a wide variety of diseases associated with cellular immune response. Therefore, it has become a vital need to be able to specifically determine the Neo concentration in human serum. Molecularly imprinted cryogels have come into prominence among other affinity systems by
Okan, Zenger +4 more
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Biopterin and neopterin in human saliva
Life Sciences, 1989Presence of biopterin and neopterin in human saliva was investigated by HPLC after iodine oxidation in acidic medium. Concentrations of biopterin and neopterin (M +/- SEM) were 1.271 +/- 0.254 and 0.358 +/- 0.075 ng per ml, respectively, in saliva of apparently healthy young male adults, ages 20 to 22 years (n = 9).
S, Katoh +3 more
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Neopterin as a potential biomarker in neuropsychiatry
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020The importance of finding predictors or biomarkers of neuropsychiatric pathology, as well as methods of its prevention, treatment and early diagnosis is beyond question. The level of neopterin in body fluids is one of the possible biomarkers. Increased levels of neopterin in biological fluids (e.g., serum, cerebrospinal fluid or urine) are closely ...
Yu E, Shilov, I I, Miroshnichenko
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Molecular Immunology, 2005
Neopterin is well established as a reliable marker in HIV-1 infection. Neopterin concentrations measured in urine or serum indicate sensitively the course and progression of the disease as well as efficacy of anti-retroviral therapy. The main trigger for neopterin production is Th1-type cytokine interferon-gamma.
Barbara, Wirleitner +3 more
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Neopterin is well established as a reliable marker in HIV-1 infection. Neopterin concentrations measured in urine or serum indicate sensitively the course and progression of the disease as well as efficacy of anti-retroviral therapy. The main trigger for neopterin production is Th1-type cytokine interferon-gamma.
Barbara, Wirleitner +3 more
openaire +2 more sources