Results 81 to 90 of about 22,017 (305)

Neopterin Concentrations in Colon Dialysate

Pteridines, 2001
Increased production of neopterin in humans is indicative for an activated cellular immune response. The intestinal immune system encounters an enormous amount of infectious agents or injurious substances evoking a cellular immune response. The objective
Ledjeff E., Artner-Dworzak E., Witasek A., Fuchs D., Hausen A.   +4 more
doaj   +1 more source

Neopterin as Tumour Marker Serum and Urinary Neopterin Concentrations in Malignant Diseases [PDF]

Clinical Chemistry and Laboratory Medicine, 1986
Serum and urinary neopterin concentrations were measured in 142 patients suffering from various malignant diseases. Increased serum and urinary neopterin levels were found in 48% and 55% of patients respectively. Neopterin showed sufficient sensitivity in the detection of haematological disorders and hypernephroma, whereas the sensitivity of neopterin ...
Kuzmits, R., Ludwig, H., Legenstein, Elisabeth, Szekeresz, T., Kratzik, C., Hofbauer, J.   +5 more
openaire   +3 more sources

Neopterin Levels and Indoleamine 2,3-Dioxygenase Activity as Biomarkers of Immune System Activation and Childhood Allergic Diseases

Annals of Laboratory Medicine, 2019
Background Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase with interferon-gamma (IFN-γ ...
S. Ünüvar, D. Erge, Bilge Kilicarslan, Harika Gözde Gözükara Bağ, F. Çatal, G. Girgin, T. Baydar   +6 more
semanticscholar   +1 more source

Evaluating miRNA Sequencing and Integrative Proteomics for Identifying Plasma miRNAs as Potential Pharmacodynamic Biomarkers of IFNβ‐1a Biologics

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT We used miRNA sequencing to identify candidate plasma pharmacodynamic (PD) biomarkers of interferon beta‐1a (IFNβ‐1a) biologics and explored miRNA‐mRNA targeted protein relationships and networks to support identified miRNA candidates. Plasma samples from 36 healthy subjects from a placebo‐controlled randomized single‐dose clinical study with ...
Mai Mehanna, Lakshmi Manasa Chekka, Barry A. Rosenzweig, Deepti P. Samarth, Esraa G. Mohamed, Isaac Raplee, Catherine Sullenberger, Erica Decker, Sarah J. Schrieber, Yow‐Ming Wang, Jeffry Florian, Paula L. Hyland   +11 more
wiley   +1 more source

Interventions for neurocognitive dysfunction [PDF]

, 2017
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core   +2 more sources

Association Between Neopterin Production and other Parameters in a Population of Blood Donors

Pteridines, 2002
Neopterin is released from human monocyte-derived macrophages preferentially upon stimulation with the Thlcell cytokine interferon-γ. In humans, increased concentrations of neopterin in serum and urine have been found in viral infections including human ...
Schennach Harald, Murr Christian, Gächter Elmar, Mayersbach Peter, Schönitzer Diether, Fuchs Dietmar   +5 more
doaj   +1 more source

Neopterin production in relation to COVID-19 in the Haut-Ogooué Province, Gabon [PDF]

, 2023
Serge Ely Dibakou, Chérone Nancy Mbani-Mpega-Ntigui, Sandrine Lydie Oyegue-Liabagui, Désiré Otsaghe Ekore, Yasmine Okome Nguema, Jean Bernard Lékana-Douki, Barthélémy Ngoubangoye   +6 more
openalex   +1 more source

Low‐dose total skin electron beam therapy in erythrodermic mycosis fungoides and Sézary syndrome: Results From the Prospective S‐MISR Study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 12, Page 1534-1542, December 2025.
Summary Background Erythrodermic mycosis fungoides (eMF) and Sézary syndrome (SS) often show delayed and non‐durable clinical responses to systemic therapies. Patients and Methods A total of 35 patients with eMF or SS were treated with total skin electron beam therapy (TSEBT).
Khaled Elsayad, Christian Kandler, Jan Jakob Siats, Niklas Pepper, Moritz Fabian Danzer, Gabor Dobos, Elisabeth Livingstone, Susanne Melchers, Johannes Kleemann, Julia Hyun, Claudia Pföhler, Peter von den Driesch, Jan P. Nicolay, Rudolf Stadler, Hans Theodor Eich   +14 more
wiley   +1 more source

Plasma total neopterin and neopterin levels are significantly elevated in stroke patients before carotid endarterectomy surgery

Pteridines
Atherosclerosis is an inflammatory disease where activated immune cells are recruited into the artery wall forming artery plaques. Interferon-γ released by T-cells causes macrophage synthesis and release of 7,8-dihydroneopterin, an antioxidant and CD36 ...
Raajasekar Siddarth, Roake Justin, Cameron Vicky, Benson Ruth, Pilbrow Anna, Gieseg Steven   +5 more
doaj   +1 more source

Systemic Immune Activation, Anemia and Thrombocytosis in Breast Cancer Patients Treated by Doxorubicin and Paclitaxel

Pteridines, 2006
Increased urinary concentrations of neopterin, an indicator of systemic immune activation, have been reported only in a minority of patients with breast cancer. We determined urinary neopterin by high-performance liquid chromatography in 78 patients with
Melichar Bohuslav, Solichova Dagmar, Melicharova Karolina, Urminska Hana, Ryska Ales, Cermanova Melanie   +5 more
doaj   +1 more source