Results 51 to 60 of about 12,655 (161)

Successful Surgical Repair of Ventricular Septal Defect in a Child With Ocular Myasthenia Gravis and History of Myeloid Sarcoma Post‐HSCT: A Multidisciplinary Approach

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT A 3 year‐old child with ocular myasthenia gravis and a history of hematopoietic stem cell transplantation underwent successful ventricular septal defect repair through carefully coordinated multidisciplinary management. The tailored anesthetic approach and infection‐control strategy enabled smooth recovery without neuromuscular or immunologic ...
Shuhan Rong, Wanyu Xu, Xin Li
wiley   +1 more source

Efficacy and safety of neostigmine on treating gastrointestinal dysmotility in severe acute pancreatitis patients: study protocol for a randomized controlled trial

Trials, 2023
Background Acute pancreatitis is a serious threat to human health and gastrointestinal dysmotility is a common complication for acute pancreatitis patients, resulting in delayed feeding, oral feeding intolerance, paralytic ileus, and abdominal ...
Han Sun, Yaqi Sheng, Tiekuan Du, Huadong Zhu   +3 more
doaj   +1 more source

Nipocalimab‐aahu (IMAAVY) for Generalized Myasthenia Gravis: Redefining Treatment With FcRn Inhibition

Medicine Advances, Volume 3, Issue 4, Page 374-376, December 2025.
FDA approval of IMAAVY (nipocalimab) marks a major advancement in the management of generalized myasthenia gravis (gMG). Clinical trial data showed significant improvements in MG‐ADL scores, especially in AChR‐positive patients, while also highlighting its favorable safety profile, potential for subcutaneous self‐administration, and greater ...
Muhammad Affan Abid, Malaika Manzoor, Reham Jamal, Humaiz Ahmed   +3 more
wiley   +1 more source

Polymyxin B Induced Acute Diaphragmatic Paralysis: A Case Report Based on Therapeutic Drug Monitoring

Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Polymyxin B (PMB), a last‐resort antibiotic for multidrug‐resistant Gram‐negative infections, carries significant neurotoxicity risks that remain underrecognized in clinical practice. Here, we present a case of life‐threatening diaphragmatic paralysis induced by PMB in a patient with extensive neck and mediastinal infections caused by ...
Yunli Zhang, Xiaogang Tang, Yan Li, Xia Su, Xiaohong Zhong, Zhai Huang   +5 more
wiley   +1 more source

Transdermal nitroglycerine enhances postoperative analgesia of intrathecal neostigmine following abdominal hysterectomies

Indian Journal of Anaesthesia, 2010
This study was carried out to assess the effect of nitroglycerine (transdermal) on intrathecal neostigmine with bupivacaine on postoperative analgesia and note the incidence of adverse effects, if any.
Fareed Ahmed, Ashish Garg, Vipul Chawla, Mamta Khandelwal   +3 more
doaj   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

Journal of Gastroenterology and Hepatology, Volume 40, Issue 12, Page 2842-2856, December 2025.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang, Theng Yi Tay, Simon Gibbs, Ola Niewiadomski   +3 more
wiley   +1 more source

Characterization of Novel POLG Mutations in Mitochondrial Encephalomyopathy: Pathogenic Validation and Comprehensive Genetic Profiling

Brain and Behavior, Volume 15, Issue 11, November 2025.
We report a 32‐year‐old female patient with SANDO syndrome (a subtype of mitochondrial encephalomyopathy), who carries two heterozygous POLG mutations: a novel c.3297G>C and a known c.1774C>T. The neuronal models expressing these mutations demonstrated mitochondrial dysfunction, thereby confirming their pathogenicity.
Fanjing Zhou, Jiang Chen, Tingzheng Zhang, Fengnan Niu, Jinglong Hu, Yun Xu, Meijuan Zhang   +6 more
wiley   +1 more source

Laparoscopic Cholecystectomy in a Young Female With Wolff‐Parkinson‐White Syndrome: Anesthetic Implications and Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT This case highlights that, with thorough preoperative assessment, continuous careful intraoperative monitoring, precise anesthetic selection, and multidisciplinary coordination, patients with incidentally detected Wolff–Parkinson–White (WPW) syndrome can safely undergo laparoscopic cholecystectomy under general anesthesia, demonstrating that ...
Sunil Bhatta, Sukriti Pandit
wiley   +1 more source

Decline in gut motility of cerebral palsy patients after a triggering event: A discussion on invasive versus conservative management

JPGN Reports, Volume 6, Issue 4, Page 360-367, November 2025.
Abstract Objectives Patients with cerebral palsy (CP) often have gastrointestinal dysmotility. An inciting event, such as infection, may lead to progressive decline in bowel motility and episodes of acute pediatric intestinal pseudo‐obstruction (PIPO).
Zoe Saenz, Elizabeth Reynolds, Jamie E. Anderson, Payam Saadai, Maheen Hassan   +4 more
wiley   +1 more source

Low-dose spinal neostigmine further enhances the analgesic effect of spinal bupivacaine combined with epidural dexamethasone, following orthopedic surgery

Journal of Research in Medical Sciences, 2014
Background: Opioids are considered mainstream for combined spinal-epidural anesthesia, but frequently limited by adverse effects. The aim of this study was to examine whether low-dose spinal neostigmine, epidural dexamethasone or their combination ...
Gabriela Rocha Lauretti, Fabricio S Veloso, Antonio T Kitayama, Anita Leocadia Mattos   +3 more
doaj