Results 61 to 70 of about 13,100 (169)

Non-neuronal cholinergic stimulation favors bone mass accrual

Frontiers in Physiology
IntroductionNon-neuronal cholinergic receptors are expressed in immune cells and their stimulation has been shown to regulate the secretion of several cytokines.
Faleh Tamimi, Faleh Tamimi, Faleh Tamimi, Hazem Eimar, Sharifa Alebrahim, Lina Abu-Nada, Garthiga Manickam, Ahmed Ebraheem Al Subaie, Iskandar Tamimi, Monzur Murshed, Monzur Murshed, Monzur Murshed   +11 more
doaj   +1 more source

Clinical Variability and Genotype‐Driven Outcomes in CHRND‐Related Congenital Myasthenic Syndrome

European Journal of Neurology, Volume 33, Issue 9, September 2026.
Clinical variability in CHRND‐related congenital myasthenic syndrome ranges from isolated ocular involvement to severe neonatal‐onset disease with respiratory insufficiency. In a multicenter cohort of nine patients, ocular symptoms represented the core phenotype, while disease severity was influenced by genotype and presumed residual acetylcholine ...
David Muhmann, Göknur Haliloğlu, Maria Antonia Grimalt, Damjan Osredkar, Ana Vesperinas Castro, Silvia Cerezo Corredera, Angela Abicht, Adalet Elçin Yıldız, Johann Böhm, Ulrike Schara‐Schmidt, Anja Troha Gergeli, Berta Estevez‐Arias, Elena Cortes Vicente, Andres Nascimento, Adela Della Marina, Daniel Natera‐de Benito, Andreas Roos   +16 more
wiley   +1 more source

Topical Donepezil for Cholinergic Modulation in Chronic Wound Repair

Wound Repair and Regeneration, Volume 34, Issue 5, September/October 2026.
ABSTRACT Chronic wounds result from combined defects in vascular perfusion, inflammatory resolution, and epithelial repair. The skin's non‐neuronal cholinergic system (NNCS), formed by keratinocytes, endothelial cells, fibroblasts, and immune cells that synthesise and respond to acetylcholine (ACh), helps coordinate these processes through muscarinic ...
Hui‐Qi Qu, Charlly Kao, Hakon Hakonarson   +2 more
wiley   +1 more source

EFFECTS OF INTRANASAL NEOSTIGMINE ON ESOPHAGEAL MOTILITY IN MAN

, 1992
The effects of intranasally administered neostigmine on oesophageal peristalsis and lower oesophageal sphincter tone were investigated in 21 healthy volunteers.
C. BENVENUTI, A. DELIA, M. NICORA, F. CALLIONI, D. FOSCHI, L. CASTOLDI   +5 more
core   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, Volume 13, Issue 47, 24 August 2026.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Effectiveness of intramuscular neostigmine to accelerate bladder emptying after spinal anesthesia

, 2018
Tjokorda Gde Agung Senapathi, Made Wiryana, I Made Subagiartha, I Putu Pramana Suarjaya, I Made Gede Widnyana, Ida Bagus Krisna Jaya Sutawan, A A Gde Putra Semara Jaya, Andri Thewidya Department of Anesthesiology and Intensive Care, Sanglah Hospital ...
Wiryana M, Widnyana IMG, Thewidya A, Senapathi TGA, Sutawan IBKJ, Jaya AAGPS, Subagiartha IM, Suarjaya IPP   +7 more
core  

Association of Demographic, Clinical, and Environmental Factors With Disease Severity in Adult Myasthenia Gravis: A Multicenter Cross‐Sectional Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
The disease severity of adult myasthenia gravis is influenced by multiple factors. Our results showed that gender, age at onset, BMI, onset symptoms, thymoma, and thymectomy were correlated with disease scores. Additionally, environmental exposures, including latitude, altitude, sunlight duration, PM2.5, education, and monthly household income, also ...
Haoran Liu, Jingsi Wang, Wenjia Zhu, Ting Chang, Hongxi Chen, Chao Sun, Rongjing Guo, Zhe Ruan, Fangfang Bi, Jing Li, Jianwen Wang, Shu Zhang, Qi Wen, Yaye Wang, Yun Li, Nairong Xie, Yuting Jiang, Yan Lu, Li Di, Min Xu, Min Wang, Hai Chen, Xinmei Wen, Jianying Duo, Yue Huang, Huiyu Feng, Hongyu Zhou, Yuwei Da   +27 more
wiley   +1 more source

Low-dose spinal neostigmine further enhances the analgesic effect of spinal bupivacaine combined with epidural dexamethasone, following orthopedic surgery

Journal of Research in Medical Sciences, 2014
Background: Opioids are considered mainstream for combined spinal-epidural anesthesia, but frequently limited by adverse effects. The aim of this study was to examine whether low-dose spinal neostigmine, epidural dexamethasone or their combination ...
Gabriela Rocha Lauretti, Fabricio S Veloso, Antonio T Kitayama, Anita Leocadia Mattos   +3 more
doaj  

Ofatumumab Treatment for Refractory Generalized Myasthenia Gravis Post‐Lung Adenocarcinoma Resection: A Case Report and Mechanistic Insight

Immunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
ABSTRACT Background Myasthenia gravis (MG), an autoimmune neuromuscular disorder, may rarely coexist with malignancies such as lung cancer. Case Presentation This case report presents the first documented use of ofatumumab, a fully human anti‐CD20 monoclonal antibody, in a 75‐year‐old female with acetylcholine receptor (AChR)‐antibody‐positive ...
Xia Long, Yanwen Xu, Juan Xiong, Wenfeng Peng, Jinhua Qiu, Yanxia Zhou   +5 more
wiley   +1 more source

POSTOPERATIVE ANALGESIA INDUCED BY INTRATHECAL NEOSTIGMINE OR BETHANECHOL IN RATS

, 2009
P>Cholinergic agonists and acetylcholinesterase inhibitors, such as neostigmine, produce a muscarinic receptor-mediated antinociception in several animal species that depends on activation of spinal cholinergic neurons.
DIAS, T. B., PRADO, W. A.
core   +1 more source