Results 71 to 80 of about 62,474 (297)

Macular Hole Formation Following Intravitreal Aflibercept for Neovascular Age-Related Macular Degeneration

Case Reports in Ophthalmology, 2022
This case report describes full-thickness macular hole formation after intravitreal aflibercept injections for the treatment of macular neovascularization in neovascular age-related macular degeneration (AMD).
Yasmin Ali Said, David Vanwynsberghe, Julie Jacob   +2 more
doaj   +1 more source

Eye Disease Prediction using Ensemble Learning and Attention on OCT Scans [PDF]

arXiv, 2023
Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain, particularly when combined with Optical Coherent Technology (OCT) imaging.
arxiv  

Complement C3 variant and the risk of age-related macular degeneration [PDF]

, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM, Bird, AC, Clayton, DG, Deary, IJ, Dhillon, B, Genetic Factors AMD Study G, Hayward, C, Khan, JC, Matharu, BK, Moore, AT, Morgan, J, Redmond, E, Sepp, T, Shahid, H, Thurlby, DA, Wright, AF, Yates, JRW   +16 more
core   +1 more source

Anemia and retinopathy of prematurity: A narrative review

Pediatric Investigation, EarlyView.
Anemia in infants who are at greatest risk of developing severe retinopathy of prematurity is almost universal. There is plausible evidence in the literature correlating anemia with severe ROP. However, the relationship is complex, and further study is needed to better understand the potential molecular mechanisms for anemia‐associated ROP.
Minali Prasad, David Dombrovsky, Stephen P. Christiansen, Ellen C. Ingolfsland   +3 more
wiley   +1 more source

Comparison of the efficacy and safety of SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration

Scientific Reports
To compare the efficacy and safety of the proposed aflibercept biosimilar SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration, this randomized, double-masked, parallel-group, multicenter study was conducted in ...
Se Woong Kang, Jaehwan Choi, Veeral S. Sheth, Agnieszka Nowosielska, Marta Misiuk-Hojlo, András Papp, David M. Brown, Jae-Ho Lee, Yoreh Barak   +8 more
doaj   +1 more source

Evaluation of Transfer Learning for Classification of: (1) Diabetic Retinopathy by Digital Fundus Photography and (2) Diabetic Macular Edema, Choroidal Neovascularization and Drusen by Optical Coherence Tomography [PDF]

arXiv, 2019
Deep learning has been successfully applied to a variety of image classification tasks. There has been keen interest to apply deep learning in the medical domain, particularly specialties that heavily utilize imaging, such as ophthalmology. One issue that may hinder application of deep learning to the medical domain is the vast amount of data necessary
arxiv  

Morphometric analyses of the visual pathways in macular degeneration [PDF]

, 2015
Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated. Previous reports have shown that this affects the grey matter of the primary visual cortex, but possible effects on the preceding visual pathway structures have not been ...
arxiv   +1 more source

Defining a Minimum Set of Standardized Patient-centered Outcome Measures for Macular Degeneration [PDF]

, 2016
Purpose To define a minimum set of outcome measures for tracking, comparing, and improving macular degeneration care. Design Recommendations from a working group of international experts in macular degeneration outcomes registry development and patient ...
Barthelmes, D. (Daniel), Blumenkranz, M. (Mark), Cheung, G. (Gemmy), Gillies, M.C. (Mark), Haller, J. (Julia), Johnston, R. (Robert), Kim, R. (Ramasamy), Klaver, C.C.W. (Caroline), McKibbin, M. (Martin), Ngah, N.F. (Nor Fariza), Pershing, S. (Suzann), Rodrigues, I.A. (Ian A.), Shankar, D. (Dato), Sprinkhuizen, S.M. (Sara M.), Tamura, H. (Hiroshi), Tufail, A. (Adnan), Weng, C.Y. (Christina Y.), Westborg, I. (Inger), Yelf, C. (Catherine), Yoshimura, N.   +19 more
core   +2 more sources

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

IL-18 is not therapeutic for neovascular age-related macular degeneration [PDF]

Nature Medicine, 2014
Up to 50 million people worldwide are afflicted with the devastating blinding disease age-related macular degeneration (AMD)1–3. The vast majority of patients have the currently untreatable “dry” or atrophic form of AMD, characterized by NLRP3 inflammasome-driven degeneration of the retinal pigment epithelium (RPE) supportive cell layer4,5. Blockade of
Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, BastosCarvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J   +23 more
openaire   +5 more sources