Results 71 to 80 of about 30,955 (215)

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

Acta Ophthalmologica, EarlyView.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger, Safa Mohanna, Sohrab Ferdowsi, Sonja Simon‐Zoula, Oliver Pfäffli, Christoph Amstutz, Lucas M. Bachmann, Michael A. Thiel, Martin K. Schmid   +8 more
wiley   +1 more source

Macular Hole Formation Following Intravitreal Aflibercept for Neovascular Age-Related Macular Degeneration

Case Reports in Ophthalmology, 2022
This case report describes full-thickness macular hole formation after intravitreal aflibercept injections for the treatment of macular neovascularization in neovascular age-related macular degeneration (AMD).
Yasmin Ali Said, David Vanwynsberghe, Julie Jacob   +2 more
doaj   +1 more source

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed, Jesper Høiberg Erichsen, Afrouz Ahmadzadeh, Lars Morten Holm, Line Kessel, Daniella Bach‐Holm   +5 more
wiley   +1 more source

Comparison of the efficacy and safety of SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration

Scientific Reports
To compare the efficacy and safety of the proposed aflibercept biosimilar SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration, this randomized, double-masked, parallel-group, multicenter study was conducted in ...
Se Woong Kang, Jaehwan Choi, Veeral S. Sheth, Agnieszka Nowosielska, Marta Misiuk-Hojlo, András Papp, David M. Brown, Jae-Ho Lee, Yoreh Barak   +8 more
doaj   +1 more source

Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration [PDF]

, 2017
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy. They can also be useful in clinical practice for monitoring disease progression, evaluation of treatment efficacy, and risk assessment in multifactorial diseases ...
Dammeier, S. (Sascha), Delcourt, C. (Cécile), Hollander, A.I. (Anneke), Hoyng, C.B. (Carel), Jong, E.K. (Eiko) de, Kersten, E. (Eveline), Klaver, C.C.W. (Caroline), Lengyel, I. (Imre), Paun, C.C. (Codrut), Peto, T. (Tünde), Schellevis, R.L. (Rosa L.), Ueffing, M. (Marius)   +11 more
core   +1 more source

Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate longitudinal changes in choroidal thickness (CT) in highly myopic eyes and their correlation with myopic maculopathy progression and visual outcomes. Methods Retrospective cohort study on 1228 eyes from 781 highly myopic patients with a minimum 5‐year follow‐up (mean 11.5 ± 3.1 years).
Matteo Mario Carlà, Francesco Boselli, Federico Giannuzzi, Emanuele Crincoli, Fiammetta Catania, Agnese Maria Perugini, Gloria Gambini, Stanislao Rizzo, Carlos Mateo   +8 more
wiley   +1 more source

Spotlight on Faricimab in the Treatment of Wet Age-Related Macular Degeneration: Design, Development and Place in Therapy

Drug Design, Development and Therapy, 2022
Archana A Nair, Avni P Finn, Paul Sternberg Jr Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USACorrespondence: Paul Sternberg Jr, Chair and G. W.
Nair AA, Finn AP, Sternberg P Jr
doaj  

Retinal pigment epithelial tears after intravitreal bevacizumab injection for exudative age-related macular degeneration. [PDF]

, 2008
PURPOSE: To determine the incidence of and the risk factors for the development of retinal pigment epithelial (RPE) tears after intravitreal bevacizumab (Avastin) injection for the treatment of exudative age-related macular degeneration (AMD). METHODS: A
Brod, Roy, Fischer, David, Garg, Sunir, Kim, David, Lane, R Gary, Maguire, Joseph   +5 more
core   +2 more sources

The prechoroidal cleft in neovascular age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular neovascularization
Niels J. Brouwer, T. H. Khanh Vu, Yvonne De Jong‐Hesse, Elon H. C. van Dijk   +3 more
wiley   +1 more source

Deep Learning in Neovascular Age-Related Macular Degeneration

Medicina
Background and objectives: Age-related macular degeneration (AMD) is a complex and multifactorial condition that can lead to permanent vision loss once it progresses to the neovascular exudative stage.
Enrico Borrelli, Sonia Serafino, Federico Ricardi, Andrea Coletto, Giovanni Neri, Chiara Olivieri, Lorena Ulla, Claudio Foti, Paola Marolo, Mario Damiano Toro, Francesco Bandello, Michele Reibaldi   +11 more
doaj   +1 more source