Results 121 to 130 of about 36,146 (282)

Gene Transfer for Neovascular Age-Related Macular Degeneration [PDF]

open access: yesHuman Gene Therapy, 2011
Age-related macular degeneration (AMD) is a complex disease that has two phases: a degenerative phase often referred to as nonneovascular AMD (non-NVAMD) or dry AMD and a phase dominated by growth of new blood vessels in the subretinal space, referred to as NVAMD or wet AMD.
openaire   +2 more sources

Pegaptanib sodium for neovascular age-related macular degeneration: clinical experience in the UK

open access: yesClinical Ophthalmology, 2008
Sobha Sivaprasad, Nachiketa Acharya, Phil HykinMoorfields Eye Hospital, London, UKAbstract: The pathogenesis of age-related macular degeneration (AMD) is unclear, but it can take either a neovascular/exudative/wet form, characterized by choroidal ...
Sobha Sivaprasad   +2 more
doaj  

Successful treatment of neovascular age-related macular degeneration following single bevacizumab failure using aflibercept in a vitrectomized eye

open access: yesClinical Ophthalmology, 2014
Paul Hahn Duke Eye Center, Duke University Medical Center, Durham, NC, USA Abstract: Intravitreal anti-vascular endothelial growth factor (VEGF) pharmacotherapy in vitrectomized eyes remains a challenge due to the reduced half-life of these agents ...
Hahn P
doaj  

Subretinal fibrosis secondary to neovascular age-related macular degeneration: mechanisms and potential therapeutic targets

open access: yesNeural Regeneration Research
Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular degeneration. It causes local damage to photoreceptors, retinal pigment epithelium, and choroidal vessels, which leads to permanent central vision loss of patients with ...
Jingxiang Zhang   +5 more
doaj   +1 more source

Early SUSVIMO in Neovascular Age-Related Macular Degeneration: Real Word Case Report and Clinical Implications

open access: yesInternational Medical Case Reports Journal
Jakob Pericak,1,2 Eric K Chin,3,4 David RP Almeida2 1State University of New York at Geneseo, Geneseo, NY, USA; 2Erie Retina Research & Center for Advanced Surgical Exploration, Erie, PA, USA; 3Retina Consultants of Southern California, Redlands, CA, USA;
Pericak J, Chin EK, Almeida DRP
doaj  

Relationships between Patient-Reported Outcome Measures and Clinical Measures in Naïve Neovascular Age-Related Macular Degeneration Patients Treated with Intravitreal Ranibizumab

open access: yesPharmaceuticals
Our objective was to evaluate changes in patient-reported outcome measures using the NEI-VFQ 25 questionnaire during a treat and extend regimen in naive neovascular Age-Related Macular Degeneration patients, and its correlation with anatomical and ...
Pablo Almuiña-Varela   +9 more
doaj   +1 more source

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