Results 171 to 180 of about 13,840,459 (217)
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Macular translocation for neovascular age-related macular degeneration
Cochrane Database of Systematic Reviews, 2008Macular translocation has been proposed by vitreoretinal surgeons to displace the neuroretinal tissue onto healthy retinal pigment epithelium and choroid when the macula has been invaded by subretinal neovascularisation.This review aims at assessing the effectiveness of macular translocation for preserving or improving vision in patients with ...
Eandi CM +2 more
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Imaging in Neovascular Age-Related Macular Degeneration
Seminars in Ophthalmology, 2011Imaging plays an essential role in the diagnosis and treatment of age-related macular degeneration (AMD). This review describes the imaging modalities most commonly employed by ophthalmologists caring for patients with neovascular AMD. Imaging modalities discussed include fluorescein angiography, optical coherence tomography, indocyanine green ...
Adam J, Gess +2 more
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Age-related Macular Degeneration and Choroidal Neovascularization
American Journal of Ophthalmology, 1993The neovascular variant of age-related macular degeneration is amenable to laser photocoagulation treatment within well-defined guidelines established by clinical trials. However, only a limited number of patients meet eligibility criteria for this form of treatment, principally because of the ill-defined, or occult nature, of the choroidal ...
K B, Freund +2 more
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Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration [PDF]
New England Journal of Medicine, 2011 Clinical trials have established the efficacy of ranibizumab for the treatment of neovascular age-related macular degeneration (AMD). In addition, bevacizumab is used off-label to treat AMD, despite the absence of similar supporting data.In a multicenter, single-blind, noninferiority trial, we randomly assigned 1208 patients with neovascular AMD to ...
Daniel Martin +2 more
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Ranibizumab for neovascular age-related macular degeneration
American Journal of Health-System Pharmacy, 2008The pharmacology, pharmacokinetics, clinical efficacy, safety, pharmacoeconomics, and place in therapy of ranibizumab are reviewed.Ranibizumab is the humanized fragment of the murine monoclonal antibody that binds all the active forms of the vascular endothelial growth factor, leading to the inhibition of the neovascular process underlying age-related ...
Luis Javier, Hernandez-Pastor +3 more
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Hyperopia and Neovascularization in Age-related Macular Degeneration
Ophthalmology, 1993Refractive errors for phakic eyes of patients referred with age-related macular degeneration were reviewed to determine whether some range of refractive error might be a risk factor for the neovascular form.The authors compared refractive errors of 198 patients with unilateral neovascular disease with refractive errors of 129 patients with bilateral ...
M A, Sandberg +4 more
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Management of neovascular age-related macular degeneration
Progress in Retinal and Eye Research, 2007Neovascular age-related macular degeneration (AMD) is becoming an increasing socio-medical problem as the proportion of the aged population is continuously increasing. However, new insights in the pathogenesis of the disease offer the opportunity to develop targeted therapies that attack the disease process more successfully than ever.
Ursula M, Schmidt-Erfurth +1 more
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Neovascular Age-Related Macular Degeneration
Ophthalmology, 2013Age-related macular degeneration (AMD) progresses through early and intermediate to advanced stages, one of which is neovascular AMD (nAMD). A correct diagnosis of nAMD at an early stage is critical because unlike geographic atrophy, it can be treated with therapeutic agents.
Bianca S. Gerendas +3 more
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Neovascular Age-Related Macular Degeneration
Drugs, 2008Age-related macular degeneration (AMD) affects an estimated 14 million people worldwide, and is the leading cause of severe, irreversible vision loss in individuals over the age of 50 years in Western societies. Choroidal neovascularization (CNV), the hallmark of 'wet', 'exudative' or 'neovascular' AMD, is responsible for approximately 90% of cases of ...
Aimee V, Chappelow, Peter K, Kaiser
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Ranibizumab for Neovascular Age-Related Macular Degeneration
New England Journal of Medicine, 2006Ranibizumab--a recombinant, humanized, monoclonal antibody Fab that neutralizes all active forms of vascular endothelial growth factor A--has been evaluated for the treatment of neovascular age-related macular degeneration.In this multicenter, 2-year, double-blind, sham-controlled study, we randomly assigned patients with age-related macular ...
Philip J, Rosenfeld +6 more
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