Results 21 to 30 of about 17,658 (183)

Ranibizumab in neovascular age-related macular degeneration

open access: yesClinical Interventions in Aging, 2006
Neovascular age-related macular degeneration (AMD) is a visually devastating condition resulting from choroidal neovascularization and secondary photoreceptor loss. Ranibizumab and bevacizumab are medications that target vascular endothelial growth factor (VEGF).
T Eng, Kenneth, Peter J, Kertes
openaire   +2 more sources

Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration - the potential sources and molecular cues for their recruitment and activation

open access: yesEBioMedicine, 2018
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in developed countries. Neovascular AMD (nAMD) accounts for 90% of AMD-related vision loss.
Karis Little   +4 more
doaj   +1 more source

Aflibercept for neovascular age-related macular degeneration

open access: yesCochrane Database of Systematic Reviews, 2016
Central vision loss caused by age-related macular degeneration (AMD) is the leading cause of blindness among the elderly in developed countries. Neovascular AMD is characterized by choroidal neovascularization (CNV). Growth of new blood vessels in patients with neovascular AMD is driven by a complex process that involves a signal protein called ...
Salman, Sarwar   +9 more
openaire   +3 more sources

Brolucizumab-induced retinal vasculitis – An Indian perspective

open access: yesIndian Journal of Ophthalmology. Case Reports, 2022
The case of retinal vasculitis in a one-eyed elderly diabetic female after use of brolucizumab injection (second dose) for neovascular age-related macular degeneration.
Manpreet Brar   +4 more
doaj   +1 more source

New Therapies of Neovascular AMD beyond Anti-VEGF Injections

open access: yesVision, 2018
Neovascular age-related macular degeneration is a leading cause of vision loss among the aging population. The current standard of care to treat neovascular age-related macular degeneration is inhibiting vascular endothelial growth factor (VEGF) through ...
Greggory M. Gahn, Arshad M. Khanani
doaj   +1 more source

Unusual visual loss in a patient with exudative macular degeneration

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of marked vision loss in a patient with neovascular age-related macular degeneration after choroidal neovascular membrane (CNV) improvement and stabilization.
Enoch T. Peng, Sean D. Adrean
doaj   +1 more source

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

open access: yesAdvanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui   +3 more
wiley   +1 more source

Evaluation of Flowmetry Indicators in Patients with a Wet AMD Form during Antiangiogenic Therapy

open access: yesOftalʹmologiâ, 2019
Purpose: to assess the effect of aflibercept (Eylea; “Regeneron”, USA) intravitreal injections on ocular blood flow and intraocular pressure parameters in patients with neovascular form of age-related macular degeneration (wet AMD).
N. Yu. Yousef   +5 more
doaj   +1 more source

Quantitative Autofluorescence in Non-Neovascular Age Related Macular Degeneration

open access: yesBiomedicines, 2023
Quantitative autofluorescence (qAF8) level is a presumed surrogate marker of lipofuscin content in the retina. We investigated the changes in the qAF8 levels in non-neovascular AMD. In this prospective cohort study, Caucasians aged ≥50 years with varying
Shruti Chandra   +7 more
doaj   +1 more source

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

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