Results 71 to 80 of about 14,897 (210)

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Neovascularisation after surgery for recurrent saphenofemoral incompetence : does surgical dissection technique matter?

, 2011
The effect of the type of surgery on neovascularisation in the groin is unknown. The aim of the present study was to compare three different surgical techniques used for recurrent saphenofemoral incompetence in view of their effect on neovascularisation ...
Zehnder, T. (T.), Maeseneer, M.G.R. (Marianne) de, Mouton, WG, Mouton, W.G., de Maeseneer, Marianne, Wagner, H.E. (H.), Heim, D. (D.), Marklewitz, M.M., Friedli, S. (S.), Friedli, S, Zehnder, T, Mouton, W. G., Marklewitz, M. M., Mouton, J.W. (Johan), De Maeseneer, M. G., Wagner, H.E., Wagner, HE, Marklewitz, M.M. (M.), Marklewitz, MM, Friedli, S., Heim, D., Wagner, H. E., Zehnder, T., Heim, D, de Maeseneer, M.G.   +24 more
core   +1 more source

Ganglion cell-derived LysoPS induces retinal neovascularisation by activating the microglial GPR34-PI3K-AKT-NINJ1 axis

Journal of Neuroinflammation
Retinal neovascularisation is a major cause of blindness in patients with proliferative diabetic retinopathy (PDR). It is mediated by the complex interaction between dysfunctional ganglion cells, microglia, and vascular endothelial cells.
Lushu Chen, HuiYing Zhang, Ying Zhang, Xiumiao Li, MeiHuan Wang, Yaming Shen, Yuan Cao, Yong Xu, Jin Yao   +8 more
doaj   +1 more source

Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells

Molecules, 2017
The bioactive lipid, sphingosine 1-phosphate (S1P) binds to a family of G protein-coupled receptors, termed S1P1-S1P5. These receptors function in, for example, the cardiovascular system to regulate vascular barrier integrity and tone, the nervous system
Nigel J. Pyne, Susan Pyne
doaj   +1 more source

Kinetics of neovascularisation of splenic autotransplants in mice [PDF]

Journal of Anatomy, 1999
The aim of this study was to examine the kinetics of neovascularisation of splenic autoimplants into the abdominal cavity after splenectomy in mice. Sixty‐eight female Swiss mice were submitted to splenectomy. The spleen from each animal was sliced and the slices were implanted into the abdominal cavity.
H J, Alves, G, Viana, M M, Magalhães, R M, Arantes, P M, Coelho, J R, Cunha-Melo   +5 more
openaire   +2 more sources

Five‐Year Treatment Outcomes of Macular Oedema Secondary to Central Retinal Vein Occlusion in Routine Clinical Practice: The Fight Retinal Blindness! Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report 5‐year outcomes in a cohort of patients who received anti‐VEGF therapy for macular oedema secondary to central retinal vein occlusion (CRVO) in routine clinical practice. Methods In this retrospective observational study, 593 treatment‐naïve eyes that commenced anti‐VEGF treatment between 1 January 2010, and 2019 were ...
Katrin Rudolph, Marianna Rosso, Mark Gillies, Adrian Hunt, Louise O'Toole, Alessandro Invernizzi, David Squirrell, Hemal Mehta, Richard Barry, Pierre‐Henry Gabrielle, Daniel Barthelmes   +10 more
wiley   +1 more source

No effects of PRP on ultrasonographic tendon structure and neovascularisation in chronic midportion Achilles tendinopathy

, 2011
To assess whether a platelet-rich plasma (PRP) injection leads to an enhanced tendon structure and neovascularisation, measured with ultrasonographic techniques, in chronic midportion Achilles tendinopathy.
Tol, J. L., Weinans, H., Schie, Hans, Weir, Adam, Verhaar, J. A. N., de Vos, Robert-Jan, Weinans, HH, de Vos, R. J., Verhaar, Jan, Weir, A., van Schie, H. T. M., Tol, JL   +11 more
core   +1 more source

Interleukin-18 an Emerging Player in the Age-related Macular Degeneration Treatment: A Narrative Review [PDF]

Journal of Clinical and Diagnostic Research
The goal of this review was to investigate the role of chronic inflammation in age-related disorders, with a particular focus on the possible use of Interleukin-18 (IL-18) as an immunotherapy for Age-related Macular Degeneration (AMD). The literature has
Srashti Jain, Sachin Daigavane
doaj   +1 more source

Evaluation of the Safety and Therapeutic Range of Nanosecond Laser Treatment in Rabbits

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Subthreshold, nanosecond laser therapy has potential as a treatment for age‐related macular degeneration; however, the therapeutic range and safety profile have not been fully documented. In this study, rabbits were used for a preclinical assessment of nanosecond laser treatment.
Glyn Chidlow, John P. M. Wood, Weng Onn Chan, Robert J. Casson   +3 more
wiley   +1 more source

Nonclassical ultrasonographic presentation of retinal detachment: Blindness in a 21‐year‐old gelding with equine recurrent uveitis

Equine Veterinary Education, EarlyView.
Summary A 21‐year‐old gelding, with a history of equine recurrent uveitis, was presented for a chronic nonhealing corneal ulcer. Ophthalmic examination of the right eye revealed a deep corneal ulcer, with the presence of corneal neovascularisation, mild diffuse corneal oedema and hypopyon. Additionally, the gelding was blind from the affected eye.
M. van Heule, A. Khachadoorian, M. Wichtel, B. N. Lillie, D. Kenney, A. Merchán Muñoz   +5 more
wiley   +1 more source