Results 71 to 80 of about 19,198 (302)

Neovascularisation after surgery for recurrent saphenofemoral incompetence : does surgical dissection technique matter?

, 2011
The effect of the type of surgery on neovascularisation in the groin is unknown. The aim of the present study was to compare three different surgical techniques used for recurrent saphenofemoral incompetence in view of their effect on neovascularisation ...
Zehnder, T. (T.), Maeseneer, M.G.R. (Marianne) de, Mouton, WG, Mouton, W.G., de Maeseneer, Marianne, Wagner, H.E. (H.), Heim, D. (D.), Marklewitz, M.M., Friedli, S. (S.), Friedli, S, Zehnder, T, Mouton, W. G., Marklewitz, M. M., Mouton, J.W. (Johan), De Maeseneer, M. G., Wagner, H.E., Wagner, HE, Marklewitz, M.M. (M.), Marklewitz, MM, Friedli, S., Heim, D., Wagner, H. E., de Maeseneer, Marianne G., Zehnder, T., Heim, D   +24 more
core   +1 more source

Delivery of nano‐formulated drugs to solid tumours is selectively increased by co‐application of the vascular disrupting agent CA4P

British Journal of Pharmacology, EarlyView.
Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski, Constanze Heise, Stefanie Sperling, Jasmin Hotz, Danica Bajic, Marina Rubey, Kathrin Klar, Georg Höfner, Julien Vollaire, Veronique Josserand, Jean‐Luc Coll, Oliver Thorn‐Seshold, Petar Marinković, Julia Thorn‐Seshold   +13 more
wiley   +1 more source

Neutrophil pyroptosis regulates corneal wound healing and post‐injury neovascularisation

Clinical and Translational Medicine
Rationale The cornea is a unique structure that maintains its clarity by remaining avascular. Corneal injuries can lead to neovascularisation (CNV) and fibrosis and are the third most common cause of blindness worldwide. Objective Corneal injuries induce
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Shanzhi Wang, Kyung Eun Lee, Bingchuan Geng, Jongsoo Kim, Bao Zhao, Qiang Wang, Haitao Wen, Heather L. Chandler, Hua Zhu   +12 more
doaj   +1 more source

Closure of the saphenous opening after saphenofemoral junction disconnection: An anatomical barrier against postoperative neovascularization [PDF]

Ain-Shams Journal of Surgery, 2010
Introduction: Neovascularisation at the sapheno-femoral junction (SFJ) ligation site in the groin may occur within one year after great saphenous vein (GSV) surgery.
Hesham Adel Alaa-Eldin, Sherif Essam Tawfik   +1 more
doaj   +1 more source

Neovascularisation of the meniscus with angiogenin. An experimental study in rabbits

, 1991
Angiogenin, a potent blood vessel inducing protein, was implanted into experimentally injured menisci of 75 New Zealand white rabbits. Localised neovascularisation occurred in 52% of the angiogenin-treated animals, and in 9% of the controls ...
TV King, BL Vallee
core   +1 more source

Enhanced VEGF signalling mediates cerebral neovascularisation via downregulation of guidance protein ROBO4 in a rat model of diabetes

Diabetologia, 2017
Aims/hypothesisDiabetes promotes cerebral neovascularisation via increased vascular endothelial growth factor (VEGF) angiogenic signalling. Roundabout-4 (ROBO4) protein is an endogenous inhibitor of VEGF signalling that stabilises the vasculature.
M. Abdelsaid, Maha Coucha, Sherif Hafez, Abdul Yasir, Maribeth H. Johnson, A. Ergul   +5 more
semanticscholar   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Surgical treatment of peripapillary choroidal neovascularisation [PDF]

British Journal of Ophthalmology, 2007
To report the functional and morphological outcome of surgical treatment of peripapillary choroidal neovascularisation due to age-related macular degeneration.Consecutive interventional case series of eight patients with extensive peripapillary choroidal neovascularisation and accompanying haemorrhage who underwent subretinal surgery including ...
S, Aisenbrey, F, Gelisken, P, Szurman, K U, Bartz-Schmidt   +3 more
openaire   +2 more sources

Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial.

The Lancet, 2013
BACKGROUND Bevacizumab has been suggested to have similar effectiveness to ranibizumab for treatment of neovascular age-related macular degeneration. The Inhibition of VEGF in Age-related choroidal Neovascularisation (IVAN) trial was designed to compare ...
U. Chakravarthy, S. Harding, C. Rogers, S. Downes, A. Lotery, L. Culliford, B. Reeves   +6 more
semanticscholar   +1 more source