Results 71 to 80 of about 11,092 (181)

Delivery of nano‐formulated drugs to solid tumours is selectively increased by co‐application of the vascular disrupting agent CA4P

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4663-4674, August 2026.
Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski   +13 more
wiley   +1 more source

Ultrasound-guided electrocoagulation of neovascularisation for persistent patellar tendinopathy in athletes: a cohort study of 25 patients with a mean follow-up of 5 years from the SANTI Study Group

open access: yesBMJ Open Sport & Exercise Medicine
Background Patellar tendinopathy (PT) is a common condition characterised by persistent patellar tendon pain and dysfunction, particularly in athletes. Neovascularisation is frequently observed in the PT and is associated with increased pain.
Bertrand Sonnery-Cottet   +8 more
doaj   +1 more source

Emerging techniques to treat corneal neovascularisation [PDF]

open access: yesEye, 2011
Neovascularisation is a major cause of visual loss in a number of ophthalmic diseases. This review aims to outline the basic regulators of vessel growth in corneal neovascularisation. An understanding of the underlying principles of physiological and pathophysiological vascular development helps to appreciate current approaches to prevent or treat ...
openaire   +2 more sources

Anti-VEGF Therapy and the Retina: An Update

open access: yesJournal of Ophthalmology, 2015
Ocular angiogenesis and macular oedema are major causes of sight loss across the world. Aberrant neovascularisation, which may arise secondary to numerous disease processes, can result in reduced vision as a result of oedema, haemorrhage, and scarring ...
Vikas Tah   +7 more
doaj   +1 more source

Ganglion cell-derived LysoPS induces retinal neovascularisation by activating the microglial GPR34-PI3K-AKT-NINJ1 axis

open access: yesJournal of Neuroinflammation
Retinal neovascularisation is a major cause of blindness in patients with proliferative diabetic retinopathy (PDR). It is mediated by the complex interaction between dysfunctional ganglion cells, microglia, and vascular endothelial cells.
Lushu Chen   +8 more
doaj   +1 more source

Le profil épidémiologique de la néovascularisation cornéenne : à propos de 165 cas. The epidemiological profile of corneal neovascularization : about 165 cases

open access: yesJournal de la Société Marocaine d’Ophtalmologie, 2019
Résumé Introduction. -La néovascularisation cornéenne  est l’apparition des néovaisseaux dans le stroma cornéen normalement avasculaire. Les pathologies néovasculaires cornéennes sont fréquentes dans notre contexte  et représentent un problème de santé ...
D. Fofana   +7 more
doaj   +1 more source

Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction Myopia has become a big public health problem in certain parts of the world. Sight-threatening complications like choroidal neovascularisation membranes occur in up to 10% of pathological myopia, and natural history studies show a trend ...
Kumaran Neruban   +2 more
doaj   +1 more source

Transplantation of Amniotic Membrane to the Subretinal Space in Pigs

open access: yesStem Cells International, 2012
Purpose. To investigate the effect of transplanted amniotic membrane (AM) on subretinal wound healing. Methods. Nine Danish Landrace pigs had surgical removal of retinal pigment epithelium (RPE) and mechanical damage of Bruch’s membrane (BM) and served ...
Jens Folke Kiilgaard   +3 more
doaj   +1 more source

Diagnosis and Monitoring of Choroidal Osteoma through Multimodal Imaging

open access: yesCase Reports in Medicine, 2014
A 16-year-old Caucasian female with a 6-month history of decreased visual acuity and metamorphopsia in the left eye is reported. The fundus of the left eye revealed a well defined lesion in the macula region.
Theodoros Empeslidis   +7 more
doaj   +1 more source

Neovascular age-related macular degeneration: disease pathogenesis and current state of molecular biomarkers predicting treatment response—a scoping review

open access: yesBMJ Open Ophthalmology
Age-related macular degeneration is a major cause of blindness, and the development of anti-vascular endothelial growth factor (VEGF) intravitreal treatments has revolutionised the management of the disease.
Nikolaos Dervenis   +2 more
doaj   +1 more source

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