Results 211 to 220 of about 34,072 (291)

Reimagining Oncologic Drugs in Atherosclerosis: Emerging Mechanisms and Therapeutic Potential. [PDF]

open access: yesBiomedicines
Liu G   +5 more
europepmc   +1 more source

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study develops a biomimetic bilayer scaffold based on gelatin methacryloyl‐ciprofloxacin/polycaprolactone‐collagen (GelMA‐CIP/PCL‐COL), designed to release EGF and TGFβ3 in a controlled manner. The GelMA‐CIP@PVA‐EGF/PCL‐COL@PVA‐TGFβ3 scaffold currently demonstrates sustained delivery of growth factors for 28 days, mechanical properties similar to ...
Hilal Yilmaz   +11 more
wiley   +1 more source

From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting

open access: yesMacromolecular Materials and Engineering, EarlyView.
This review explores recent advances in 3D bioprinting, emphasizing printing technologies, bioink design, and emerging strategies such as cryogenic printing. Key challenges in biocompatibility, vascularization, and scalability are discussed, alongside opportunities for clinical translation.
Muhammad Wajid Ullah   +9 more
wiley   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

open access: yesMed Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang   +13 more
wiley   +1 more source

Mathematical Modeling and Optimal Control of Combined Virotherapy and Adoptive T Cell Therapy for Cancer Treatment

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this study, we investigate the synergistic roles of adoptive T cell therapy (ACT), specifically using tumor‐infiltrating lymphocytes (TILs) and oncolytic virus (OV) therapy in enhancing cancer treatment efficacy. While OVs can initiate tumor destruction, they often fail to achieve complete tumor eradication or generate a strong antitumor ...
Salaheldin Omer   +2 more
wiley   +1 more source

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