Results 231 to 240 of about 26,618 (266)

PATHOLOGY BEYOND NEOVASCULARIZATION

Retina, 2009
Control of choroid neovascularization may be important but insufficient to preserve long-term vision threatened by age-related macular degeneration. A retrospective analysis of patients who were early participants in anti-vascular endothelial growth factor studies, other pathologic processes, particularly fibrosis and atrophy, have participated in ...
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LACQUER CRACK FORMATION AND CHOROIDAL NEOVASCULARIZATION IN PATHOLOGIC MYOPIA

Retina, 2008
To clarify the characteristics of choroidal neovascularization (CNV) due to myopic CNV (mCNV) and the relation to lacquer crack (LC) formation.Thirty-seven eyes with mCNV underwent fluorescein angiography (FA) and indocyanine green angiography (ICGA) using Heidelberg Retina Angiograph 2 (HRA2; Heidelberg, Germany). mCNV was detected by FA and ICGA; LCs
Yasushi, Ikuno, Kaori, Sayanagi, Kaori, Soga, Miki, Sawa, Fumi, Gomi, Motokazu, Tsujikawa, Yasuo, Tano   +6 more
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Microglia in pathological neovascularization in the retina

2017
INTRODUCTION. Mononuclear phagocytes (e.g. microglia, macrophages) have been characterized as potential mediators of retinal neovascularization and degeneration. In vivo assessments of mononuclear phagocyte behavior in animals provides an important insight into disease that improves the understanding of pathological mechanisms and helps to approach new
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INTRAVITREAL RANIBIZUMAB FOR CHOROIDAL NEOVASCULARIZATION COMPLICATING PATHOLOGIC MYOPIA

Retina, 2010
The purpose of this study was to evaluate the efficacy of intravitreal injections of ranibizumab in choroidal neovascularization secondary to pathologic myopia.A prospective case series of 32 eyes of 32 patients affected with choroidal neovascularization secondary to pathologic myopia treated by intravitreal injections of ranibizumab.
Lalloum F, Souied EH, Bastuji Garin S, Puche N, QUERQUES , GIUSEPPE, Glacet Bernard A, Coscas G, Soubrane G, Leveziel N.   +8 more
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Neuropilin-1 is upregulated in Sjögren’s syndrome and contributes to pathological neovascularization

Histochemistry and Cell Biology, 2012
Neuropilin-1 (NRP1) is a transmembrane co-receptor for members of the vascular endothelial growth factor family. Recent studies revealed an important role of NRP1 in angiogenesis and progression of many diseases. The role of NRP1 in the development of Sjögren's syndrome (SS), one of the most common rheumatic diseases, has not yet been investigated ...
Sisto M, Lisi S, LOFRUMENTO, Dario Domenico, D'Amore M, Ribatti D.   +4 more
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Inhibition of Pathological Retinal Neovascularization by α-Defensins.

Blood, 2005
Abstract Proliferative retinopathies, such as those complicating prematurity and diabetes, are major causes of blindness. A prominent feature of these retinopathies is excessive neovascularization, which is orchestrated by the hypoxia-induced vascular endothelial growth factor (VEGF) stimulating endothelial cells, and the integrin ...
Matina Economopoulou, Hans-Peter Hammes, Klaus T. Preissner, Jacek Lubkowski, Yasmina Bdeir, Franz Fogt, Douglas B. Cines, Khalil Bdeir, Triantafyllos Chavakis   +8 more
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Endomucin is necessary for pathologic retinal neovascularization in vivo

The FASEB Journal, 2017
Many ocular pathologies, including wet age‐related macular degeneration (AMD) and the retinopathy of prematurity, are characterized by abnormal neovascularization. Endomucin‐1 (EMCN), is an endothelial cell‐specific, sialic‐rich glycoprotein. We have shown that EMCN is necessary for VEGF‐mediated proliferation, migration and tube formation by human ...
Patricia A. D'Amore, Cindy A. Park‐Windhol, Magali Saint‐Geniez   +2 more
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[Using thalidomide against pathological neovascularization].

Harefuah, 2003
Thalidomide was first used during the 50's-60's, especially for morning sickness in pregnant women. It was found to be a powerful teratogen only years later and was banned from use. At the same time it was found to have anti-inflammatory and anti-angiogenic properties and was approved as treatment for leprosy. As such, thalidomide might be used against
Arik, Eisenkraft, Shai, Luria, Eyal, Robenshtok, Ariel, Hourvitz   +3 more
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INTRAVITREAL BEVACIZUMAB FOR EXTRAFOVEAL CHOROIDAL NEOVASCULARIZATION SECONDARY TO PATHOLOGIC MYOPIA

Retina, 2013
To assess the effects of intravitreal bevacizumab injections in the treatment of extrafoveal choroidal neovascularization (CNV) associated with pathologic myopia.Patients diagnosed with pathologic myopia complicated by extrafoveal CNV were considered in this prospective, open-label interventional study.
Parodi MB, Iacono P, Papayannis A, Kontadakis S, Cascavilla ML, Zucchiatti I, BANDELLO , FRANCESCO   +6 more
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Antivascular Endothelial Growth Factor for Choroidal Neovascularization in Pathologic Myopia

2010
Choroidal neovascularization (CNV) is the most common vision-threatening macular complication in pathologic myopia (PM) being detectable in 4-11% of the affected eyes. Treatment of PM-related CNV is still controversial. Intravitreal injections of antivascular endothelial growth factor molecules are able to inhibit the vascular endothelial growth factor
Battaglia Parodi M, Iacono P, Bandello F.   +2 more
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