Results 231 to 240 of about 26,143 (267)

Characteristics of Periconus Choroidal Neovascularization in Pathologic Myopia

American Journal of Ophthalmology, 2011
To examine the clinical characteristics of periconus choroidal neovascularizations (CNVs) in eyes with pathologic myopia.Retrospective observational case series.We reviewed the medical records of 260 eyes of 254 patients with a myopic CNV and selected those with a periconus CNV.
Natsuko, Nagaoka, Noriaki, Shimada, Wakako, Hayashi, Kengo, Hayashi, Muka, Moriyama, Takeshi, Yoshida, Takashi, Tokoro, Kyoko, Ohno-Matsui   +7 more
openaire   +2 more sources

LACQUER CRACK FORMATION AND CHOROIDAL NEOVASCULARIZATION IN PATHOLOGIC MYOPIA

Retina, 2008
To clarify the characteristics of choroidal neovascularization (CNV) due to myopic CNV (mCNV) and the relation to lacquer crack (LC) formation.Thirty-seven eyes with mCNV underwent fluorescein angiography (FA) and indocyanine green angiography (ICGA) using Heidelberg Retina Angiograph 2 (HRA2; Heidelberg, Germany). mCNV was detected by FA and ICGA; LCs
Yasushi, Ikuno, Kaori, Sayanagi, Kaori, Soga, Miki, Sawa, Fumi, Gomi, Motokazu, Tsujikawa, Yasuo, Tano   +6 more
openaire   +2 more sources

PATHOLOGY BEYOND NEOVASCULARIZATION

Retina, 2009
Control of choroid neovascularization may be important but insufficient to preserve long-term vision threatened by age-related macular degeneration. A retrospective analysis of patients who were early participants in anti-vascular endothelial growth factor studies, other pathologic processes, particularly fibrosis and atrophy, have participated in ...
openaire   +2 more sources

53BP1 Deficiency Promotes Pathological Neovascularization in Proliferative Retinopathy

Thrombosis and Haemostasis, 2019
AbstractThe replication stress inflicted on retinal endothelial cells (ECs) in the context of hypoxia-induced pathological neovascularization during proliferative retinopathy is linked with activation of the deoxyribonucleic acid (DNA) repair response.
Troullinaki, María, García-Martín, Rubén, Sprott, David, Klotzsche-von Ameln, Anne, Grossklaus, Sylvia, Mitroulis, Ioannis, Chavakis, Triantafyllos, Economopoulou, Matina   +7 more
openaire   +3 more sources

Microglia in pathological neovascularization in the retina

2017
INTRODUCTION. Mononuclear phagocytes (e.g. microglia, macrophages) have been characterized as potential mediators of retinal neovascularization and degeneration. In vivo assessments of mononuclear phagocyte behavior in animals provides an important insight into disease that improves the understanding of pathological mechanisms and helps to approach new
openaire   +1 more source

INTRAVITREAL RANIBIZUMAB FOR CHOROIDAL NEOVASCULARIZATION COMPLICATING PATHOLOGIC MYOPIA

Retina, 2010
The purpose of this study was to evaluate the efficacy of intravitreal injections of ranibizumab in choroidal neovascularization secondary to pathologic myopia.A prospective case series of 32 eyes of 32 patients affected with choroidal neovascularization secondary to pathologic myopia treated by intravitreal injections of ranibizumab.
Lalloum F, Souied EH, Bastuji Garin S, Puche N, QUERQUES , GIUSEPPE, Glacet Bernard A, Coscas G, Soubrane G, Leveziel N.   +8 more
openaire   +3 more sources

Neuropilin-1 is upregulated in Sjögren’s syndrome and contributes to pathological neovascularization

Histochemistry and Cell Biology, 2012
Neuropilin-1 (NRP1) is a transmembrane co-receptor for members of the vascular endothelial growth factor family. Recent studies revealed an important role of NRP1 in angiogenesis and progression of many diseases. The role of NRP1 in the development of Sjögren's syndrome (SS), one of the most common rheumatic diseases, has not yet been investigated ...
Sisto M, Lisi S, LOFRUMENTO, Dario Domenico, D'Amore M, Ribatti D.   +4 more
openaire   +4 more sources

Endomucin is necessary for pathologic retinal neovascularization in vivo

The FASEB Journal, 2017
Many ocular pathologies, including wet age‐related macular degeneration (AMD) and the retinopathy of prematurity, are characterized by abnormal neovascularization. Endomucin‐1 (EMCN), is an endothelial cell‐specific, sialic‐rich glycoprotein. We have shown that EMCN is necessary for VEGF‐mediated proliferation, migration and tube formation by human ...
Patricia A. D'Amore, Cindy A. Park‐Windhol, Magali Saint‐Geniez   +2 more
openaire   +1 more source

Inhibition of Pathological Retinal Neovascularization by α-Defensins.

Blood, 2005
Abstract Proliferative retinopathies, such as those complicating prematurity and diabetes, are major causes of blindness. A prominent feature of these retinopathies is excessive neovascularization, which is orchestrated by the hypoxia-induced vascular endothelial growth factor (VEGF) stimulating endothelial cells, and the integrin ...
Matina Economopoulou, Hans-Peter Hammes, Klaus T. Preissner, Jacek Lubkowski, Yasmina Bdeir, Franz Fogt, Douglas B. Cines, Khalil Bdeir, Triantafyllos Chavakis   +8 more
openaire   +1 more source

[Using thalidomide against pathological neovascularization].

Harefuah, 2003
Thalidomide was first used during the 50's-60's, especially for morning sickness in pregnant women. It was found to be a powerful teratogen only years later and was banned from use. At the same time it was found to have anti-inflammatory and anti-angiogenic properties and was approved as treatment for leprosy. As such, thalidomide might be used against
Arik, Eisenkraft, Shai, Luria, Eyal, Robenshtok, Ariel, Hourvitz   +3 more
openaire   +1 more source