During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu +5 more
wiley +1 more source
Special Issue: Molecular Mechanisms and Treatment of Retinal Diseases. [PDF]
Lee D, Vitiello L.
europepmc +1 more source
Summary Background Same‐site recurrence at the sapheno‐femoral junction (SFJ) takes up a large amount of the daily practice of phlebologists. Follow‐up data for high‐ligation and stripping (HL/S) of the great saphenous vein (GSV) are quite heterogenous and incoherent.
Thomas Hummel +11 more
wiley +1 more source
Clinical characteristics and treatment outcomes of bilateral myopic macular neovascularization in high myopic patients. [PDF]
Lim SH +5 more
europepmc +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Myopic and Glaucomatous Optic Neuropathy in Highly Myopic Eyes: A Practical Framework for Diagnosis, Monitoring, and Management. [PDF]
Akada M, Numa S, Tsujikawa A.
europepmc +1 more source
Double Myopic Choroidal Neovascular Membranes (CNVMs): A Case Report. [PDF]
Perente A +4 more
europepmc +1 more source
Imaging of the retinal hypoxia: A journey from oxygen microelectrode to the first hypoxia imaging in the living retina. [PDF]
Uddin MI.
europepmc +1 more source
Multimodal imaging of stellate nonhereditary idiopathic foveomacular retinoschisis with midperipheral retinoschisis and microvasculopathy. [PDF]
Bourdin A +5 more
europepmc +1 more source
Identification of a Tenochondral Ossification Sequence Producing Heterotopic Ossification in Human Achilles Tendinopathy. [PDF]
Li H, Boyce B, Ulici V, Ciufo D, Cao C.
europepmc +1 more source

