Results 101 to 110 of about 91,571 (261)

Ferrochelatase regulates retinal neovascularization

, 2020
Ferrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo.
Pran Babu, Sardar Pasha Sheik, White, Darcy, Corson, Timothy W.   +2 more
core   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

PRECURSORS OF TYPE 3 NEOVASCULARIZATION

, 2013
PURPOSE: To study the advent of exudative age-related macular degeneration in uninvolved fellow eyes of patients with unilateral Type 3 neovascularization and to investigate the precursors at the site of lesion development.
Giuseppe Querques, Rocio Blanco, FORTE, RAIMONDO, Lea Querques, Nathalie Massamba, Eric H. Souied   +5 more
core   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Sema3f Protects Against Subretinal Neovascularization In Vivo

, 2017
Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti ...
Samuel B. Burnim, Ludwig, Franziska, Reuer, Tristan, Yan Gong, Andreas Stahl, Ye Sun, Schlunck, Günther, Walz, Johanna M., Raffael Liegl, Daniel Böhringer, Burnim, Samuel B., Anima Bühler, Günther Schlunck, Bühler, Anima, Zhang, Peipei, Liu, Chi-Hsiu, Tristan Reuer, Smith, Lois E.H., Liegl, Raffael, Peipei Zhang, Stahl, Andreas, Sun, Ye, Hansjürgen Agostini, Chi-Hsiu Liu, Johanna M. Walz, Lange, Clemens, Steven S. Meng, Clemens Lange, Agostini, Hansjürgen, Böhringer, Daniel, Cakir, Bertan, Meng, Steven S., Gong, Yan, Lois E.H. Smith, Bertan Cakir, Franziska Ludwig   +35 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Lactadherin promotes VEGF-dependent neovascularization

, 2005
International audienceVascular endothelial growth factor (VEGF)-induced blood vessel growth is involved in both physiological and pathological angiogenesis and requires integrin-mediated signaling.
Jean-Sébastien Silvestre, Sylvia Heeneman, Christophe Houbron, Silvestre, J.-S., Alain Delcayre, Hamard, G., Mallat, Z., Olivier Blanc-Brude, Heeneman, S., Alain Tedgui, Tedgui, A., Théry, C., Radia Tamarat, Micheline Duriez, Aguilar, B., Boddaert, J., Tamarat, R., Sebastian Amigorena, Bernard Lévy, Jacques Boddaert, Delcayre, A., Houbron, C., Régine Merval, Ghislaine Hamard, Duriez, M., Amigorena, S., Ziad Mallat, Michel Clergue, Barbara Aguilar, Blanc-Brude, O., Clotilde Théry, Clergue, M., Lévy, B., Merval, R.   +33 more
core   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

A case of subretinal neovascularization treated with intravitreal ranibizumab in a patient with idiopathic juxtafoveal retinal telangiectasis

, 2008
Dimitrios Karagiannis1, Ilias Georgalas2, Ioannis Ladas2, Parikakis Eustratios1, Panagiotis Mitropoulos11Second Department of Ophthalmiatrion Eye Hospital, NHS, Athens, Greece; 2Department of Ophthalmology, “G.Genimatas” General Hospital ...
Dimitrios Karagiannis, Parikakis Eustratios, Panagiotis Mitropoulos, Ioannis Ladas, Ilias Georgalas   +4 more
core  

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source