Results 101 to 110 of about 134,088 (312)

Choroidal neovascularization secondary to Best’s vitelliform macular dystrophy in two siblings of a Malay family

, 2014
Koh Alisa-Victoria,1 Tan Jin-Poi,1 Ismail Shatriah,1 Embong Zunaina,1 Nor Fariza Ngah2 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 2Department of Ophthalmology, Hospital Selayang ...
Zunaina E, Jin-Poi T,Shatriah I, Ngah NF, Alisa-Victoria K   +3 more
core  

Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. [PDF]

, 2018
Purpose Neovascularization is a major cause of blindness in various ocular diseases. Bioactive sphingosine 1-phosphate (S1P), synthesized by two sphingosine kinases (Sphk1, Sphk2), emerged as a key player in a multitude of cellular processes ...
Koch, Alexander, Devraj, Kavi, Lars-Olof Hattenbach, Vutukuri, Rajkumar, Yannick Schreiber, Huwiler, Andrea, Katrin Schröder, Kavi Devraj, Popp, Rüdiger, Alexander Koch, Martin Stumpf, Pfeilschifter, Josef, Nerea Ferreirós, Andrea Huwiler, Jeanette Eresch, Eresch, Jeanette, Hattenbach, Lars-Olof, Waltraud Pfeilschifter, Rüdiger Popp, Stumpf, Martin, Rajkumar Vutukuri, Ferreirós, Nerea, Pfeilschifter, Waltraud, Josef Pfeilschifter, Schreiber, Yannick, Schröder, Katrin   +25 more
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Photodynamic therapy for neovascular age-related macular degeneration

Philippine Journal of Ophthalmology, 2005
Background: In neovascular age-related macular degeneration (ARMD) new vessels grow under the retina, distorting vision and leading to scarring. This is exacerbated if the blood vessels leak.
Richard P.L. Wormald, MA, MB, BCh, MSc, FRCS, FRCOphth, Jennifer R Evans, PhD, Katherine S Henshaw, Liam L Smeeth, MD   +3 more
doaj  

CCR3 and Choroidal Neovascularization

PLoS ONE, 2011
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly in industrialized countries. The "wet" AMD, characterized by the development of choroidal neovacularization (CNV), could result in rapid and severe loss of central vision.
Yiwen Li, Deqiang Huang, Xin Xia, Zhengying Wang, Lingyu Luo, Rong Wen   +5 more
openaire   +4 more sources

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

Bevacizumab for the Treatment of Corneal Neovascularization

, 2011
Corneal neovascularization (NV) is a severe complication associated with inflammatory or infectious disorders of the cornea. NV may lead to severe reduction in visual acuity and poor prognosis for corneal transplantation and excimer laser refractive ...
CHEN, WEI-LI;CHEN, YAN-MING;CHU, HSIAO-SANG;TSAI, TZU-YUN;HU, FUNG-RONG, 陳偉勵;陳彥名;朱筱桑;蔡紫筠;胡芳蓉   +1 more
core  

Ferrochelatase regulates retinal neovascularization

, 2020
Ferrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo.
Pran Babu, Sardar Pasha Sheik, White, Darcy, Corson, Timothy W.   +2 more
core   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

Advanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang, Yiyuan Kang, Shulin Lai, Chunyi Wang, Guixin He, Kehui Jian, Suhan Yin, Xiner Tan, Xinru Zhou, Wenjing Liu, Fujian Zhao, Jia Liu, Longquan Shao   +12 more
wiley   +1 more source

PRECURSORS OF TYPE 3 NEOVASCULARIZATION

, 2013
PURPOSE: To study the advent of exudative age-related macular degeneration in uninvolved fellow eyes of patients with unilateral Type 3 neovascularization and to investigate the precursors at the site of lesion development.
Giuseppe Querques, Rocio Blanco, FORTE, RAIMONDO, Lea Querques, Nathalie Massamba, Eric H. Souied   +5 more
core   +1 more source