Results 161 to 170 of about 150,746 (305)

Single‐Cell RNA Sequencing and Spatial Multiomics Unveil Microglia–Mural Interactions Underlying Notoginsenoside R1 Against Ischemic Stroke

open access: yesiMetaMed, EarlyView.
Integrated scRNA‐seq and spatial multiomics provide single‐cell and spatial insights into the neuroprotective effects of NGR1, a clinically validated bioactive compound from Panax notoginseng. NGR1 was associated with a shift in microglial transcriptional states away from ischemia‐associated pro‐inflammatory Adam8hi microglia and toward the protective ...
Qikun Zhao   +10 more
wiley   +1 more source

Microglia in retinal vascular diseases: inflammatory mechanism and therapeutic target. [PDF]

open access: yesInt J Ophthalmol
Xu J   +6 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu   +5 more
wiley   +1 more source

Biomarkers of native liver survival and portal hypertension in biliary atresia

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective To evaluate the prognostic value of noninvasive markers Aspartate Aminotransferase to Platelet Ratio Index (APRi) and Infantile Biliary Atresia Liver Fibrosis score (iBALF), as well as the histological Ishak fibrosis score, as predictors of native liver survival (NLS) and portal hypertension (PH) in children with biliary atresia (BA)
Karyne Sumico de Lima Uyeno Jordão   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy