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Neovascular glaucoma (NVG) is a secondary ocular pathological condition resulting from a myriad of ocular and systemic conditions with retinal ischemia as a mediator in over 95% of cases. NVG is caused by the growth of a fibrovascular membrane secondary to a local angiogenic stimulus over the trabecular meshwork obstructing aqueous outflow.
Shane J, Havens, Vikas, Gulati
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Intraocular neovascularization.
An important character of the eye is transparency, so intraocular neovascularization, which is fragile and likely to result in hemorrhage, would cause a functional disorder of the eye and contribute to loss of vision associated with such diseases as retinopathy of prematurity, diabetic retinopathy, retinal vein occlusion, and age-related macular ...
Yoshida, A. +3 more
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Dual Suppression of Oxidative Stress and JAK/STAT3 Signaling Attenuates Inflammation-Driven Corneal Neovascularization. [PDF]
Corneal neovascularization is sustained by oxidative stress and inflammatory STAT3 signaling. A macrophage membrane‐cloaked nanozyme, Sta@MSR, combines ruthenium‐mediated ROS scavenging with Stattic‐mediated STAT3 inhibition. Delivered as eye drops, Sta@MSR enhances ocular retention and corneal penetration, reduces inflammatory and angiogenic responses,
Li Q +12 more
europepmc +2 more sources
Ocular neovascularization [PDF]
Retinal and choroidal vascular diseases constitute the most common causes of moderate and severe vision loss in developed countries. They can be divided into retinal vascular diseases, in which there is leakage and/or neovascularization (NV) from retinal vessels, and subretinal NV, in which new vessels grow into the normally avascular outer retina and ...
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Neovascular glaucoma (NVG) is a severely blinding, intractable disease. The objective of this review is to provide detailed information on its basic and clinical aspects, to enable us to manage it logically. Therefore, its causes, pathogenesis and pathology, methods of early diagnosis and management are discussed.
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Fluorescein angiography compared to three-dimensional measurements by the retinal thickness analyzer in classic choroidal neovascularization [PDF]
Purpose: To compare and correlate imaging of classic subfoveal choroidal neovascularization (CNV) with noninvasive 3-dimensional imaging by the retinal thickness analyzer (RTA) to conventional fluorescein angiography (FA).
Strauss, R. W. +3 more
core +1 more source
Influence of aflibercept on CNV type II
The application of angiogenesis blockers is a main method of therapy for a wet form of age-r elated macular degeneration (AMD).Purpose. To determine an effect of aflibercept on morphological parameters of the retina and functional indicators of the ...
R. R. Fayzrakhmanov +3 more
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Cytokines play an integral role in pathogenesis of age-related macular degeneration (AMD). Of particular interest are the late stages of this disease, which causes progressive visual impairment.
V. V. Neroev +5 more
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Filgrastim, fibrinolysis, and neovascularization [PDF]
Segmental recanalization of chronically occluded arteries was observed in patients with chronic limb-threatening ischemia (CLTI) treated with Filgrastim, a granulocyte colony stimulating factor, every 72 h for up to a month, and an infra-geniculate programmed compression pump (PCP) for 3 h daily.
Darwin Eton +4 more
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Purpose: The purpose of this study was to explore the potential underlying mechanism of anti-vascular effects of peroxisome proliferator–activated receptor α (PPARα) agonist fenofibrate against corneal neovascularization (CNV) through the changes of ...
Tong Zhou +21 more
doaj +1 more source

