Results 21 to 30 of about 150,746 (305)

cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis [PDF]

, 2009
Background Endothelium-derived nitric oxide plays an important role for the bone marrow microenvironment. Since several important effects of nitric oxide are mediated by cGMP-dependent pathways, we investigated the role of the cGMP downstream effector ...
Feil, Robert, Hofmann, Franz, Alexandra Aicher, Michael E. Mendelsohn, Aicher, Alexandra, Michael E Mendelsohn, Mendelsohn, Michael E., Alexandra Aicher, Heeschen, Christopher, Feil, Susanne, Christopher Heeschen, Stefanie Dimmeler, Dimmeler, Stefanie, Franz Hofmann, Susanne Feil, Robert Feil   +15 more
core   +2 more sources

Therapeutic vascularization in regenerative medicine

Stem Cells Translational Medicine, 2020
Therapeutic angiogenesis, that is, the generation of new vessels by delivery of specific factors, is required both for rapid vascularization of tissue‐engineered constructs and to treat ischemic conditions.
Roberto Gianni‐Barrera, Nunzia Di Maggio, Ludovic Melly, Maximilian G. Burger, Edin Mujagic, Lorenz Gürke, Dirk J. Schaefer, Andrea Banfi   +7 more
doaj   +1 more source

Current concepts on endothelial stem cells definition, location, and markers

Stem Cells Translational Medicine, 2021
Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and regeneration of blood vessels in perfusion‐deficient tissues is a worthwhile therapeutic goal. The idea of delivering endothelial stem/progenitor cells to repair damaged
Sarah E.J. Chambers, Varun Pathak, Edoardo Pedrini, Lou Soret, Nicolas Gendron, Coralie L. Guerin, Alan W. Stitt, David M. Smadja, Reinhold J. Medina   +8 more
doaj   +1 more source

Clinical and morphological aspects of the development of secondary ophthalmic hypertension in uveal melanoma

Российский офтальмологический журнал, 2022
Ophthalmic hypertension is mostly associated with medium- or large-sized melanomas. The pathogenesis of persistent IOP elevation in uveal melanoma is not fully understood at present.   Purpose.
E. E. Grishina, G. R. Setdikova, I. D. Kim, A. M. Bogatyrev, I. A. Loskutov, E. R. Eremeeva   +5 more
doaj   +1 more source

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]

, 2012
Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
David-Alexandre Tregouet (4350982), Florian Sennlaub (64439), Xavier Guillonneau, William Raoul (64427), Sophie Krumeich (177422), Sophie Krumeich, Raoul William, Théry Clotilde, Calippe Bertrand, Salomon-Yves Cohen, Poupel Lucie, Camelo, Serge, Xavier Guillonneau (64430), Bertrand Calippe, Behar-Cohen Francine, Tregouet, David-Alexandre, Baatz, Holger, Bertrand Calippe (177425), Florian Sennlaub, Lucie Poupel, Francine Behar-Cohen, Théry, Clotilde, Sophie Lavalette (64428), Serge Camelo (177419), Calippe, Bertrand, Cohen Salomon-Yves, Lavalette Sophie, Behar-Cohen, Francine, Clotilde Théry (177438), Lavalette, Sophie, Tregouet David-Alexandre, Christophe Combadière, Combadière Christophe, Raoul, William, William Raoul, Sennlaub Florian, Salomon-Yves Cohen (177429), Baatz Holger, Guillonneau, Xavier, Nicole Keller, Keller, Nicole, Guillonneau Xavier, Camelo Serge, Nicole Keller (64429), Keller Nicole, Cohen, Salomon-Yves, David-Alexandre Tregouet, Serge Camelo, Sophie Lavalette, Holger Baatz (177431), Krumeich Sophie, Christophe Combadière (177434), Sennlaub, Florian, Combadière, Christophe, Poupel, Lucie, Krumeich, Sophie, Lucie Poupel (177410), Holger Baatz, Clotilde Théry, Francine Behar-Cohen (64434), Behar-Cohen, F., Krumeich, S., Camelo, S., Combadière, C., Guillonneau, X., Baatz, H., Sennlaub, F., Calippe, B., Poupel, L., Théry, C., Keller, N., Lavalette, S., Cohen, S.Y., Tregouet, D.A., Raoul, W.   +74 more
core   +1 more source

Studying the Factors of Human Carotid Atherosclerotic Plaque Rupture, by Calculating Stress/Strain in the Plaque, Based on CEUS Images: A Numerical Study

Frontiers in Neuroinformatics, 2020
Carotid plaque neovascularization is one of the major factors for the classification of vulnerable plaque, but the axial force effects of the pulsatile blood flow on the plaque with neovessel and intraplaque hemorrhage was unclear.
Zhenzhou Li, Yongfeng Wang, Xinyin Wu, Xin Liu, Shanshan Huang, Yi He, Shuyu Liu, Lijie Ren   +7 more
doaj   +1 more source

Ranibizumab in patients with dense cataract and proliferative diabetic retinopathy with rubeosis

Oman Journal of Ophthalmology, 2012
Background: To evaluate the safety of ranibizumab as a surgical adjunct during cataract surgery in patients with proliferative diabetic retinopathy (PDR) with rubeosis, and to evaluate the efficacy and adverse effects of ranibizumab in treating PDR with ...
Yufei Tu, Catherine Fay, Suqin Guo, Marco A Zarbin, Edward Marcus, Neelakshi Bhagat   +5 more
doaj   +1 more source

Clinical Observation of Choroidal Osteoma Using Swept-Source Optical Coherence Tomography and Optical Coherence Tomography Angiography

Applied Sciences, 2022
Choroidal neovascularization (CNV) secondary to choroidal osteoma (CO) can cause profound visual loss, but detecting CNV and the tumor’s feeder vessels using traditional fluorescent angiography imaging is challenging.
Yi Xuan, Qing Chang, Yongjin Zhang, Xiaofeng Ye, Wei Liu, Lei Li, Keyan Wang, Jian Zhou, Min Wang   +8 more
doaj   +1 more source

Metabolic Tumor Microenvironment Characterization of Contrast Enhancing Brain Tumors Using Physiologic MRI

Metabolites, 2021
The tumor microenvironment is a critical regulator of cancer development and progression as well as treatment response and resistance in brain neoplasms.
Andreas Stadlbauer, Franz Marhold, Stefan Oberndorfer, Gertraud Heinz, Max Zimmermann, Michael Buchfelder, Elisabeth Heynold, Thomas M. Kinfe   +7 more
doaj   +1 more source

Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]

, 2009
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C., Schwarz, Theresa M., Kopp, Reinhard, Huber, Stephan, Heeschen, Christopher, Herrler, Tanja, Leicht, Simon F.   +6 more
core   +1 more source