Results 91 to 100 of about 35,134 (335)
Significance of microvessel density in prostate cancer core biopsy [PDF]
Vojnosanitetski Pregled, 2015 Background/Aim. In prostate tumors, angiogenesis, measured as microvessel density, is associated with tumor stage and Gleason score. The aim of this study was determine neovascularization of prostatic adenocarcinomas in core biopsies and ...
Salapura-Dugonjić Aleksandra +3 more
doaj +1 more source
Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. [PDF]
, 2019 Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully understood. We report that inhibiting spontaneous cholinergic activity or reducing starburst amacrine
Angelopoulos, CM +8 more
core +1 more source
Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme [PDF]
, 2015 Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited.
Chan, Cecilia W. S +3 more
core +1 more source
Advanced Materials, EarlyView.Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang +9 more
wiley +1 more source
Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma
Advanced Materials, EarlyView.A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li +11 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2019 Objective To investigate the value of predicting the vulnerability of atherosclerotic plaques in assessment of intraplaque neovascularization using carotid contrast-enhanced ultrasound.
Bo-wen YU +6 more
doaj
Advanced Materials, EarlyView.The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source
Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration [PDF]
, 2015 Treatment of the neovascular form of age-related macular degeneration (AMD) has been revolutionized by the introduction of such agents as ranibizumab, bevacizumab, and aflibercept.
Agrawal, Rupesh +5 more
core +2 more sources
EMBO Molecular Medicine, 2016 Age-related macular degeneration (AMD) is a leading cause of vision loss among the elderly. AMD pathogenesis involves chronic activation of the innate immune system including complement factors and microglia/macrophage reactivity in the retina. Here, we show that lack of interferon-β signaling in the retina accelerates mononuclear phagocyte reactivity ...
Anika Lückoff +5 more
openaire +4 more sources
Multifunctional Small Intestinal Submucosa Mesh for Scarless Abdominal Wall Defect Repair
Advanced Materials Interfaces, EarlyView.a) Schematic illustration of the SIS/PCA/Mg mesh preparation. b) Schematic illustration of the repair of full‐thickness abdominal wall defects by multifunctional and degradable SIS/PCA/Mg mesh. ABSTRACT Decellularized small intestinal submucosa (SIS) mesh used for the treatment of abdominal wall defects often suffers from a high risk of recurrence due ...
Fuxin Tang +7 more
wiley +1 more source