Biologic response of inguinal hernia prosthetics: A comparative study of conventional static meshes versus 3D dynamic implants [PDF]
, 2015 Despite improvements in prosthetics and surgical techniques, the rate of complications following inguinal hernia repair remains high. Among these, discomfort and chronic pain have become a source of increasing concern among surgeons.
Aasvang +26 more
core +1 more source
Advanced Materials Technologies, EarlyView.This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun +9 more
wiley +1 more source
Retinal pigment epithelial tears after intravitreal bevacizumab injection for exudative age-related macular degeneration. [PDF]
, 2008 PURPOSE: To determine the incidence of and the risk factors for the development of retinal pigment epithelial (RPE) tears after intravitreal bevacizumab (Avastin) injection for the treatment of exudative age-related macular degeneration (AMD). METHODS: A
Brod, Roy +5 more
core +2 more sources
Oral Delivery of a Tetrameric Tripeptide Inhibitor of VEGFR1 Suppresses Pathological Choroid Neovascularization [PDF]
, 2020 Valeria Tarallo +5 more
openalex +1 more source
Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy
Advanced Robotics Research, EarlyView.Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley +1 more source
Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis [PDF]
, 2016 Age-related decreases in autophagy contribute to the progression of age-related macular degeneration (AMD). We have now studied the interaction between autophagy impaired in retinal pigment epithelium (RPE) and the responses of macrophages.
Barba, Miriam Durazo +8 more
core +2 more sources
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
Osteoprotegerin is a new regulator of inflammation and angiogenesis in proliferative diabetic retinopathy [PDF]
, 2003 Osteoprotegerin (OPG) is a novel regulator of endothelial cell function, angiogenesis, and vasculogenesis. We correlated expression levels of OPG with those of the angiogenic and inflammatory factors vascular endothelial growth factor (VEGF) and monocyte
Abu El-Asrar, Ahmed M +11 more
core +3 more sources
Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair
Advanced Science, EarlyView.A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao +7 more
wiley +1 more source
Physiological conditions influencing regenerative potential of stem cells [PDF]
, 2016 Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele +3 more
core +1 more source