Results 121 to 130 of about 34,421 (331)

Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme [PDF]

, 2015
Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited.
Chan, Cecilia W. S, Kaplan, Warren, Khachigian, Levon M, Parish, Christopher   +3 more
core   +1 more source

Photodynamic therapy with verteporfin for juxtafoveal choroidal neovascularization secondary to pathologic myopia—1-year results of a prospective series [PDF]

, 2004
Dennis S.C. Lam, D. T. L. Liu, Dorothy S.P. Fan, W W Lai, S F So, W-M Chan   +5 more
openalex   +1 more source

Vascular Analysis of Type 1, 2, and 3 Macular Neovascularization in Age-Related Macular Degeneration Using Swept-Source Optical Coherence Tomography Angiography Shows New Insights into Differences of Pathologic Vasculature and May Lead to a More Personalized Understanding [PDF]

, 2022
Henrik Faatz, Kai Rothaus, Martin Ziegler, Marius Book, B. Heimes, Daniel Pauleikhoff, Albrecht Lommatzsch   +6 more
openalex   +1 more source

Biodegradable Zinc‐Based Alloys for Guided Bone Regeneration Membranes: Feasibility, Current Status, and Future Prospects

Advanced Science, EarlyView.
Recent research has shown that biodegradable metals based on zinc (Zn) may be used as guided bone regeneration (GBR) membrane materials. This study examines their viability from the standpoints of material science and biology, reports on the state of research on Zn‐based GBR membranes, and suggests specific development plans based on the potential and ...
Kai Chen, Ping Li, Qiang Guan, Xuenan Gu, Li Zhao, Linjun Huang, Chenyang Huang, Yu Qin, Chunhao Yu, Ting Zhang, Hejia Li, Yongcan Huang, Yufeng Zheng   +12 more
wiley   +1 more source

Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model [PDF]

, 2017
Aortic valve disease (AVD) is a common condition with a progressive natural history, and presently, there are no pharmacologic treatment strategies. Elastic fiber fragmentation (EFF) is a hallmark of AVD, and increasing evidence implicates developmental ...
Aikawa, Barnette, Basalyga, Bonow, Brown-Augsburger, Brunskill, Brunskill, Chung, Fondard, Franco, Gallegos, Gapski, Ghosh, Gu, Helske, Hinton, Hinton, Holm, Ihn, Iverson, Jensen, Keane, Krenz, Liang, Lindeman, Marshall, Mercer, Mohler, Mozaffarian, Munjal, Nishimura, Nkomo, Perrotta, Poggio, Potter, Rajamannan, Rossebo, Sauls, Schmieder, Schoen, Starcher, Vesely, Wirrig, Wylie-Sears, Xiong, Xiong   +45 more
core   +2 more sources

Cerebral Organoids with Integrated Endothelial Networks Emulate the Neurovascular Unit and Mitigate Core Necrosis

Advanced Science, EarlyView.
Fumadó Navarro et al. present an optimized strategy to generate vascular‐like networks that infiltrate within cerebral organoids with promising signs of blood‐brain barrier characteristics, preserved stiffness, uniform morphology, enhanced media diffusion, and reduced necrotic core.
Josep Fumadó Navarro, Siobhan Crilly, Wai Kit Chan, Shane Browne, John O. Mason, Catalina Vallejo‐Giraldo, Abhay Pandit, Mihai Lomora   +7 more
wiley   +1 more source

Influence of subretinal fluid in advanced stage retinopathy of prematurity on proangiogenic response and cell proliferation [PDF]

, 2014
Purpose The clinical phenotype of advanced stage retinopathy of prematurity (ROP, stages 4 and 5) cannot be replicated in an animal model. To dissect the molecular events that can lead up to advanced ROP, we examined subretinal fluid (SRF) and surgically
Cyr, Desireé, Hirose, Tatsuo, Lam, Godfrey, Lashkari, Kameran, Ma, Jie, Mehta, Manisha, Ng, Tat Fong, Tawansy, Khaled A., Taylor, Andrew W.   +8 more
core  

380 Dietary Arg-Gln Dipeptide or Dha Reduces Pathological Neovascularization (NV) and Promotes Retinal Vessel Re-Growth (VR) in Mouse Model of Rop [PDF]

, 2010
Sergio Li Calzi, Lynn Shaw, N Li, Julia V. Busik, Kristin L. Morris, Josef Neu, M.B. Grant   +6 more
openalex   +1 more source

MDSCs promote pathological angiogenesis in ocular neovascular disease

Biomedicine & Pharmacotherapy
Ocular neovascular diseases, which contribute significantly to vision loss, lack effective preventive treatments. Recent studies have highlighted the significant involvement of immune cells in neovascular retinopathy. Myeloid-derived suppressor cells (MDSCs) promote the development of neovascularization, but it is unknown whether they participate in ...
Xiaojun Wu, Limei Zhong, Jun Yu, Ning Wang, Shimiao Bu, Huijuan Wang, Jie Zhang, Xianqiong Luo, Yufeng Liu, Chuan Nie   +9 more
openaire   +2 more sources

Conductive Microneedles Loaded With Polyphenol‐Engineered Exosomes Reshape Diabetic Neurovascular Niches for Chronic Wound Healing

Advanced Science, EarlyView.
This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu, Jingxian Gao, Xueling Wu, Xinxin Hao, Wenxiu Hu, Lu Han   +5 more
wiley   +1 more source