Results 141 to 150 of about 134,203 (255)

Nanoparticle-based anti-VEGF treatment for Ocular Neovascularization

Diseases like AMD and DR are the leading cause for substantial and irreversible vision loss as a direct effect of pathologic ocular neovascularization and have a significant economic impact on individuals, families, health systems and countries. Nowadays,

core  

Advancing Artificial Intelligence in Myopia Management: From Predicting Progression to Supporting Clinical Decisions

Med Research, EarlyView.
The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang, Yun Wang, Lifei Zhang, Dongmei Chen, Weijie Zhang, Fang Li, Jibo Zhou   +6 more
wiley   +1 more source

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV. [PDF]

Invest Ophthalmol Vis Sci
Zhao H, Gao B, Ding N, Zhang R, Zhou W, Song G, Li H, Wu H, Yang Y, Shao L, Dong L, Wei W.   +11 more
europepmc   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Progress in the application of laser photocoagulation therapy in the treatment of pediatric retinal diseases. [PDF]

Lasers Med Sci
Zhang Q, Chai X, Gong D, Yan Y, Zhang G, Ma G.   +5 more
europepmc   +1 more source

Choroidal neovascularization secondary to pathological myopia

World Journal of Ophthalmology, 2014
openaire   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

The expanding role of widefield imaging in clinical practice. [PDF]

Indian J Ophthalmol
Ratra D.
europepmc   +1 more source

Wyburn‐Mason Syndrome: A Case Report

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yu‐Wen Wang, Chen‐Lu Pei, Jian‐Yang Gong   +2 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

Medicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama, Michael Overduin, Khaled H. Barakat   +2 more
wiley   +1 more source