Results 161 to 170 of about 26,345 (302)

Histopathologic evidence of VEGF in early neovascular AMD: from a 1992 hypothesis to a 1994 discovery - a historical perspective. [PDF]

Int J Retina Vitreous
Dastgheib KA.
europepmc   +1 more source

Detection of choroidal neovascularization due to pathologic myopia: Optical Coherence Tomography angiography vs. Fluorescein angiography

, 2018
D. Heinrich, Katharina Rüther, K Wehrmann, Nikolaus Feucht, Chris P. Lohmann, Mathias Maier   +5 more
openalex   +1 more source

PLD1-dependent PKCγ activation downstream to Src is essential for the development of pathologic retinal neovascularization

, 2010
Qiuhua Zhang, Dong Wang, Venkatesh Kundumani‐Sridharan, Laxmisilpa Gadiparthi, Dianna A. Johnson, Gábor Tigyi, Gadiparthi N. Rao   +6 more
openalex   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Attenuation of Oxygen-Induced Neovascularization and Inflammation by Neutralizing VEGFA and/or ANG-2 With an Antibody. [PDF]

Genes Cells
Oohashi H, Iwagawa T, Abe H, Kawaji C, Inokuchi Y, Soeda T, Saita K, Aihara M, Watanabe S.   +8 more
europepmc   +1 more source

Prostaglandin E2 Promotes Pathological Retinal Neovascularization via EP4R-EGFR-Gab1 Signalling Pathway

, 2019
Zhonghong Zhang, Xubin Pan, Pengfei Zhan, Yanqiu Liu, Man Wang, Yishun Shu, Yangningzhi Wang, Wenjuan Wang, Tingting Wei, Lingpeng Zhu, Jian Zou, Xiaowei Nie, Jing Leng, Yong Yao, Tianhua Xie, Xiaolu Wang   +15 more
openalex   +1 more source

Tolerability and efficacy of chemosaturation in combination with systemic therapy for metastatic uveal melanoma

International Journal of Cancer, EarlyView.
What's New? Uveal melanoma is the most common primary intraocular cancer in adults, and up to half of patients develop metastatic disease, predominantly in the liver, where prognosis remains poor despite promising treatment options. In this study, the authors evaluated the safety and efficacy of administering systemic therapy within 40 days of liver ...
Patrick Kasteleiner, Gerd Grözinger, Jörg Schmehl, Lukas Flatz, Andrea Forschner   +4 more
wiley   +1 more source

Glucose Metabolic Enzyme PFKFB3 in Cardiopulmonary Vascular Health and Disease. [PDF]

Circ Res
Li Y, Loscalzo J, Xiao W.
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Volumetric and En Face Hyper-Reflective Henle Fiber Layer in Age-Related Macular Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Wang CX, Wang J, Hormel TT, Hwang TS, Lujan BJ, Bailey ST, Huang D, Jia Y.   +7 more
europepmc   +1 more source