Results 161 to 170 of about 34,421 (331)
Advanced Science, EarlyView.Overcoming the limitations of conventional grafts, a biomimetic trachea with two independent vascular pedicles enables rapid integration and sustained patency. This approach markedly improves survival rates, restores the epithelial barrier, and promotes regenerative pathways, presenting a transformative paradigm for clinical application.
Ziming Wang +9 more
wiley +1 more source
Mast cells promote choroidal neovascularization in a model of age-related macular degeneration
Journal of Neuroinflammation‘Wet’ age-related macular degeneration (AMD) is characterized by pathologic choroidal neovascularization (CNV) that destroys central vision. Abundant evidence points to inflammation and immune cell dysfunction in the progression of CNV in AMD. Mast cells
Rabah Dabouz +3 more
doaj +1 more source
Correction to: SCF (Stem Cell Factor) and cKIT Modulate Pathological Ocular Neovascularization [PDF]
, 2019 openalex +1 more source
Advanced Science, EarlyView.An in situ moldable GelSSO/PDA@SDF hydrogel functions as a chronotaxic signal‐amplifying biomimetic niche to restore regenerative failure in diabetic cranial defects. By sequentially releasing SDF‐1α‐loaded PDA nanoparticles and osteoinductive oligodeoxynucleotides, it orchestrates immunomodulation, progenitor recruitment, angiogenesis, and ...
Yingji Mao +5 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2010 Objective To explore the changes of vascular endothelial growth factor (VEGF), vascular endothelial growth factor⁃C (VEGF⁃C) and vascular endothelial growth factor receptor⁃3 (VEGFR⁃3) expression and their impacts on tumor cell proliferation and ...
Su⁃qin CHEN +6 more
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The Mechanism and Potential Therapeutic Strategies of Vascular Aging
AGING MEDICINE, EarlyView.The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu +4 more
wiley +1 more source
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
Pegaptanib sodium for ocular vascular disease
Indian Journal of Ophthalmology, 2007 Pegaptanib sodium (Macugen) is a selective RNA aptamer that inhibits vascular endothelial growth factor (VEGF) 165 , the VEGF isoform primarily responsible for pathologic ocular neovascularization and vascular permeability, while sparing the ...
Shukla Dhananjay +3 more
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