Results 261 to 270 of about 34,421 (331)

A Biofunctional Hydrogel/Nanofiber Bilayer Scaffold Delivering EGF and TGFβ3 for Advanced Nasal Tissue Reconstruction

Macromolecular Materials and Engineering, EarlyView.
This study develops a biomimetic bilayer scaffold based on gelatin methacryloyl‐ciprofloxacin/polycaprolactone‐collagen (GelMA‐CIP/PCL‐COL), designed to release EGF and TGFβ3 in a controlled manner. The GelMA‐CIP@PVA‐EGF/PCL‐COL@PVA‐TGFβ3 scaffold currently demonstrates sustained delivery of growth factors for 28 days, mechanical properties similar to ...
Hilal Yilmaz, Sevda Gursoy, Gulsah Torkay, Shhd Saraj, Louna Karzoun, Alpay Kose, Mert Akin Insel, Ridvan Yildirim, Ayca Bal Ozturk, Ayse Ceren Calikoglu Koyuncu, Oguzhan Gunduz, Cem Bulent Ustundag   +11 more
wiley   +1 more source

P300 Promotes RUNX1 Transcription to Regulate Autophagy and Drive Corneal Neovascularization. [PDF]

Invest Ophthalmol Vis Sci
Peng Y, Wang Q, Xu J, Li Y, Cheng C, Yu K, Yao W, Pi Y, Li J, Wu D, Wang S, Yu Y.   +11 more
europepmc   +1 more source

DDR2 alleviates retinal vaso-obliteration and pathological neovascularization by modulating microglia M1/M2 phenotypic polarization in a mouse model of proliferative retinopathy

Qinjin Dai, Wenqi Su, Zhongcheng Zhou, Jiaguo Yuan, Xinru Wei, Jin Su, Jie Zhu   +6 more
openalex   +1 more source

From Bioinks to Functional Tissues and Organs: Advances, Challenges, and the Promise of 3D Bioprinting

Macromolecular Materials and Engineering, EarlyView.
This review explores recent advances in 3D bioprinting, emphasizing printing technologies, bioink design, and emerging strategies such as cryogenic printing. Key challenges in biocompatibility, vascularization, and scalability are discussed, alongside opportunities for clinical translation.
Muhammad Wajid Ullah, Mazhar Ul‐Islam, Adeeb Shehzad, Sehrish Manan, Salman Ul Islam, Atiya Fatima, Abdullah Khamis Al‐Saidi, Mustapha El Hariri El Nokab, Juan Quevedo Sanchez, Khaled O. Sebakhy   +9 more
wiley   +1 more source

Threads of Elasticity: A Single Variant Journey Through Pseudoxanthoma Elasticum's Clinical Maze. [PDF]

Cureus
Nagarajan DR, Mani Jacob D, Kakade S.
europepmc   +1 more source

mRNA vaccination mitigates pathological retinochoroidal neovascularization in animal models

Yasuo Yanagi, Hinako Ichikawa, Long H. Nguyen, Akimasa Hayashi, Naoko Abe, Hiroshi Abe, Satoshi Uchida   +6 more
openalex   +1 more source

Vascular Endothelial Growth Factors in Eye Diseases. Pathophysiology and New Therapeutic Strategies for Retinal and Choroideal Angiogenesis (Verisuonikasvutekijöiden merkitys silmäsairauksissa. Patofysiologiaa ja uusia hoitomenetelmiä verkkokalvon ja suonikalvon angiogeneettisiin sairauksiin) [PDF]

Kinnunen, Kati
core  

Mathematical Modeling and Optimal Control of Combined Virotherapy and Adoptive T Cell Therapy for Cancer Treatment

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this study, we investigate the synergistic roles of adoptive T cell therapy (ACT), specifically using tumor‐infiltrating lymphocytes (TILs) and oncolytic virus (OV) therapy in enhancing cancer treatment efficacy. While OVs can initiate tumor destruction, they often fail to achieve complete tumor eradication or generate a strong antitumor ...
Salaheldin Omer, Hermane Mambili‐Mamboundou, Rachid Ouifki   +2 more
wiley   +1 more source

HIF1 activity in photoreceptors drives type 3 neovascularization and retinal atrophy in a new mouse model of age-related macular degeneration. [PDF]

Cell Death Dis
Geiger F, Heigl T, Merolla L, Yong M, Wögenstein GM, Govers LP, Tsioti I, Fottner A, Samardzija M, Grimm C.   +9 more
europepmc   +1 more source

Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten, LaTasha K. Crawford, Elise J. B. De, Wencheng Li, Yoshiyuki Akiyama   +4 more
wiley   +1 more source