Results 61 to 70 of about 35,134 (335)

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Macrophages inhibit neovascularization in a murine model of age-related macular degeneration. [PDF]

PLoS Medicine, 2006
Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 y of age in at least three continents. Choroidal neovascularization (CNV) is the process by which abnormal blood vessels develop underneath the retina.
Rajendra S Apte, Jennifer Richter, John Herndon, Thomas A Ferguson   +3 more
doaj   +1 more source

Traitement des membranes néovasculaires myopiques par ranibizumab : résultats à long terme. [PDF]

, 2014
Background: To report our functional results of efficacy of intravitreal ranibizumab (IVR) for submacular choroidal neovessels (CNV) in high myopia, and to compare the role of optical coherence tomography (OCT), fluorescein angiography (FA) and visual ...
LADAIQUE, M.
core  

Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]

, 2004
BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
Bhardwaj, S, De Muinck, E, Ferrara, N, Khurana, R, Martin, JF, Murakami, M, Simons, M, Yla-Herttuala, S, Zachary, I, Zhuang, Z   +9 more
core   +1 more source

Implantable anti-angiogenic scaffolds for treatment of neovascular ocular pathologies [PDF]

Drug Delivery and Translational Research, 2020
The retinal physiology can accrue oxidative damage and inflammatory insults due to age and metabolic irregularities. Two notable diseases that involve retinal and choroidal neovascularization are proliferative diabetic retinopathy and wet age-related macular degeneration.
Biplab Sarkar, Zain Siddiqui, Ka Kyung Kim, Peter K. Nguyen, Xavier Reyes, Trevor J. McGill, Vivek A. Kumar   +6 more
openaire   +2 more sources

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source

Perfil epidemiológico das aplicações intravítreas de Ranibizumab

Revista Brasileira de Oftalmologia
Resumo Objetivo: O objetivo desse trabalho é avaliar o perfil de aplicações intravítreas do Ranibizumab em uma população de adultos atendidos no Instituto Benjamin Constant, no ano de 2015, levando em consideração o efeito sobre a acuidade visual e a ...
Gabriela dos Santos Souza Barros, Alléxya Affonso Antunes Marcos, Gabriella Nogueira Moraes, Eduardo Henrique Morizot Leite, Abelardo de Souza Couto Junior   +4 more
doaj   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Imaging of Hepatocellular Carcinoma by Computed Tomography and Magnetic Resonance Imaging: State of the Art [PDF]

, 2009
Hepatocellular carcinoma (HCC) is a very frequent tumor worldwide. Its incidence is linked to the distribution of liver cirrhosis and viral hepatitis, which are the main risk factors for the development of HCC.
Herrmann, Karin A., Reiser, Maximilian F., Zech, Christoph J.   +2 more
core   +1 more source

ROS‐Triggered Microgels for Programmable Drug Release in Volumetric Muscle Loss Repair

Advanced Healthcare Materials, EarlyView.
Reduced graphene oxide‐incorporated hyaluronic acid microgels are developed as ROS‐responsive, injectable platforms for curcumin delivery in volumetric muscle loss. The microgels exhibit strong antioxidative activity, high drug‐loading capacity, and ROS‐triggered release.
Seungjun Lee, Goeun Choe, Junghyun Kim, Junggeon Park, Jia Yi Erica Kok, Jae Young Lee   +5 more
wiley   +1 more source