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Archives of Pediatrics & Adolescent Medicine, 1922 These investigations were carried out to determine the functional pathology of the nephritides in children. Little data was found in the literature when this work was begun. Since that time Hill1has reported on some fairly extensive work along this line.
Gladys L. Boyd
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A case report of tubulointerstitial nephritis and uveitis syndrome in children with an unfavorable outcome [PDF]
Childhood Kidney Diseases, 2023 Tubulointerstitial nephritis and uveitis (TINU) syndrome is defined as the occurrence of tubulointerstitial nephritis and uveitis in the absence of other systemic diseases.
Sang I Kong +2 more
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Cell Death and Disease, 2022 A major cause of proteinuria in lupus nephritis (LN) is podocyte injury, and determining potential therapeutic targets to prevent podocyte injury is important from a clinical perspective in the treatment of LN.
Fu Lv +9 more
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Molecular detection of Leptospira spp. from canine kidney tissues and its association with renal lesions [PDF]
Veterinary World, 2018 Aim: The study aimed to detect the prevalence of Leptospira spp. in kidney tissues collected during necropsy and to establish its association with renal lesions in dogs of Mumbai region.
Biswajit R. Dash +4 more
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Biomolecules, 2021 Systemic lupus erythematosus (SLE) is a chronic autoimmune illness with a growing prevalence in many populations. Few studies have examined genetic predisposition to SLE, so we aimed to examine the clinical impact of the genetic polymorphisms MECP2 ...
Safaa I. Tayel +7 more
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Frontiers in Immunology, 2023 IntroductionPathologic inflammation is a major driver of kidney damage in lupus nephritis (LN), but the immune mechanisms of disease progression and risk factors for end organ damage are poorly understood.MethodsTo characterize molecular profiles through
Andrea R. Daamen +10 more
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Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.
New England Journal of Medicine, 2020 BACKGROUND In adults with active lupus nephritis, the efficacy and safety of intravenous belimumab as compared with placebo, when added to standard therapy (mycophenolate mofetil or cyclophosphamide-azathioprine), are unknown.
R. Furie +16 more
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Immunoglobulin a vasculitis after a not so innocuous wasp bite
Indian Pediatrics Case Reports, 2022 Background: Immunoglobulin A vasculitis (IgAV), previously known as Henoch–Schonlein purpura (HSP), is the most common vasculitis in children. Previous studies have identified various triggers of IgAV, with infections being the most common.
Aditi Sharma +2 more
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Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model
Frontiers in Immunology, 2023 Aberrant activation of the innate immune system is a known driver of lupus pathogenesis. Inhibition of the inflammasome and its downstream signaling components in murine models of lupus has been shown to reduce the severity of disease. Interleukin-1 beta
Shannon N. Loftus +11 more
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Update on Lupus Nephritis: Core Curriculum 2020.
American Journal of Kidney Diseases, 2020 Systemic lupus erythematosus is a multisystem autoimmune disease that commonly affects the kidneys. Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus and a major risk factor for morbidity and mortality.
S. Parikh +3 more
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