Results 1 to 10 of about 173,599 (327)
Nature Reviews Disease Primers, 2020 Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most patients with SLE who develop LN do so within 5 years of an SLE diagnosis and, in many cases, LN is the presenting manifestation resulting in the diagnosis of SLE ...
Hans-Joachim Anders +2 more
exaly +6 more sources
The immune cell landscape in kidneys of patients with lupus nephritis
Nature Immunology, 2019 Lupus nephritis is a potentially fatal autoimmune disease for which the current treatment is ineffective and often toxic. To develop mechanistic hypotheses of disease, we analyzed kidney samples from patients with lupus nephritis and from healthy control
Deepak A Rao +2 more
exaly +2 more sources
Nature Immunology, 2019 The molecular and cellular processes that lead to renal damage and to the heterogeneity of lupus nephritis (LN) are not well understood. We applied single-cell RNA sequencing (scRNA-seq) to renal biopsies from patients with LN and evaluated skin biopsies
Evan Der +2 more
exaly +2 more sources
Children, 2022 Chronic kidney disease is a recognised complication of immunoglobulin A vasculitis, (IgAV; formerly Henoch–Schonlein purpura—HSP). The pathophysiology of IgAV and why some patients develop significant renal involvement remains largely unknown ...
Julien Marro +4 more
doaj +1 more source
Delayed Onset Minimal Change Disease as a Manifestation of Lupus Podocytopathy
Clinics and Practice, 2021 Lupus podocytopathy (LP) is an uncommon manifestation of systemic lupus erythematosus (SLE) and is not included in the classification of lupus nephritis.
Rasha Aly +3 more
doaj +1 more source
Arthritis & Rheumatology, 2023 AURORA 2 evaluated the long‐term safety, tolerability, and efficacy of voclosporin compared to placebo in patients with lupus nephritis (LN) receiving an additional two years of treatment following completion of the one‐year AURORA 1 study.
Amit Saxena +17 more
semanticscholar +1 more source
Clinical spectrum of systemic lupus erythematosus in children. Case report.
Revista de la Facultad de Medicina Humana, 2021 Systemic lupus erythematosus is an autoimmune disease with multisystem involvement, an alternating clinical course, and which constitutes a diagnostic challenge, with a greater disease activity in the pediatric age group, which also darkens its prognosis.
Giuliana Reyes-Florián +3 more
doaj +1 more source
Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.
New England Journal of Medicine, 2020 BACKGROUND In adults with active lupus nephritis, the efficacy and safety of intravenous belimumab as compared with placebo, when added to standard therapy (mycophenolate mofetil or cyclophosphamide-azathioprine), are unknown.
R. Furie +16 more
semanticscholar +1 more source
Cytomegalovirus nephritis in a lung transplant recipient: A case report
JHLT Open, 2023 Introduction: Cytomegalovirus (CMV) infections are frequent in solid organ transplant recipients and associated with increased allograft dysfunction.
François M. Carlier +2 more
doaj +1 more source
Update on Lupus Nephritis: Core Curriculum 2020.
American Journal of Kidney Diseases, 2020 Systemic lupus erythematosus is a multisystem autoimmune disease that commonly affects the kidneys. Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus and a major risk factor for morbidity and mortality.
S. Parikh +3 more
semanticscholar +1 more source