Results 101 to 110 of about 8,337 (255)

TAM pathway proteins as novel salivary biomarkers for periodontitis

Journal of Periodontology, EarlyView.
Abstract Background The identification of molecular biomarkers that help clinicians in early diagnosis is a key focus of periodontal research. The major aim of this cross‐sectional observational study was to assess whether salivary TAM pathway protein levels have the potential to discriminate between periodontally healthy or gingivitis controls and ...
Karina Mendes, Ana T. P. C. Gomes, Dimitris N. Tatakis, Tiago Marques, Marla Pinto, Pedro C. Lopes, Maria J. Correia, Nuno Rosa   +7 more
wiley   +1 more source

Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Children with inflammatory bowel disease (IBD) have an increased risk of developing kidney disorders, which may cause significant kidney function impairment (SKI) or lead to chronic kidney disease (CKD). In this study we aimed to provide insights in causes and diagnoses of SKI cases and to provide recommendations for pediatric ...
Stephanie A. Vuijk, Renz C. W. Klomberg, Tobias Schwerd, Anne M. Griffiths, Séamus Hussey, Matthew W. Carroll, Petter Malmborg, Protima Deb, Margreet Wessels, Natalia Mouratidou, Stephanie van Biervliet, Michael Friedt, Susie Minson, Femke H. M. Vrieling‐Prince, Nicholas M. Croft, Lissy de Ridder, the PIBD‐SETQuality Safety Registry collaborative group   +16 more
wiley   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

The evolving role of regulatory T cells in Sjögren's disease pathogenesis and the promise of Treg‐based therapies: A comprehensive review

Rheumatology &Autoimmunity, EarlyView.
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs, Bharath Raj Srinivasan, Himabindu Jayaprakash Narayan, Mirunalini Gobinath, Lekitha Manjunath, Mahabaleshwar Mamadapur   +5 more
wiley   +1 more source

Emergence of Ophidiomyces ophidiicola, Nannizziopsis barbatae and Paranannizziopsis in free‐ranging Australian reptiles

Australian Veterinary Journal, EarlyView.
Emerging fungal diseases pose a threat to reptiles globally. Increasing detections of onygenalean fungi, particularly Ophidiomyces ophidiicola, Nannizziopsis spp. and Paranannizziopsis spp. in clinically diseased free‐ranging reptiles, indicate likely ongoing spread within wild reptile populations.
RG Butcher, B Ng, TH Hyndman, JP Wesson, E Jones, M Williams, D Brown, E Kay, A Gillett, L Valenza, LF Grogan   +10 more
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Cutaneous and non‐cutaneous diseases due to Mycoplasma pneumoniae in children

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Mycoplasma pneumoniae (MP) is a common pathogen responsible for diverse infections in children and adolescents, primarily affecting the respiratory tract. Besides causing atypical pneumonia, MP can also lead to extrapulmonary manifestations, including mucocutaneous, hematological, neurological, cardiac, and gastrointestinal symptoms.
Hanna Lindemann, Maximilian David Mauritz, Victoria Rehmann, Michael Paulussen, Jorge Frank, Malik Aydin   +5 more
wiley   +1 more source

Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach

Internal Medicine Journal, EarlyView.
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich, W. P. Abhayaratna, R. Audehm, E. I. Ekinci, R. J. MacIsaac, A. J. Nelson, A. Sharma, C. Pollock   +7 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source