Results 11 to 20 of about 173,599 (327)
Cell Death and Disease, 2022 A major cause of proteinuria in lupus nephritis (LN) is podocyte injury, and determining potential therapeutic targets to prevent podocyte injury is important from a clinical perspective in the treatment of LN.
Fu Lv +9 more
semanticscholar +1 more source
A case report of tubulointerstitial nephritis and uveitis syndrome in children with an unfavorable outcome [PDF]
Childhood Kidney Diseases, 2023 Tubulointerstitial nephritis and uveitis (TINU) syndrome is defined as the occurrence of tubulointerstitial nephritis and uveitis in the absence of other systemic diseases.
Sang I Kong +2 more
doaj +1 more source
A Case of Henoch-Schönlein Purpura with Fulminant Complications and Its Long-term Outcome [PDF]
Childhood Kidney Diseases, 2019 Henoch-Schönlein purpura (HSP) is a systemic vasculitis characterized by purpura, arthritis, abdominal pain, and nephritis. Gastrointestinal involvement can manifest as pain, intussusception, intestinal bleeding, and intestinal perforation.
Dong Hyun Lee +4 more
doaj +1 more source
Origin of Proteinuria as Observed from Qualitative and Quantitative Analysis of Serum and Urinary Proteins [PDF]
Childhood Kidney Diseases, 2015 It is well known that proteins present in the primary urine are reabsorbed in the renal proximal tubules, and that this reabsorption is mediated via the megalin‐cubilin complex and the neonatal Fcγ receptor.
Shori Takahashi
doaj +1 more source
Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis
JCI Insight, 2022 Lupus nephritis is a serious complication of systemic lupus erythematosus, mediated by IgG immune complex (IC) deposition in kidneys, with limited treatment options. Kidney macrophages are critical tissue sentinels that express IgG-binding Fcγ receptors (
N. Richoz +13 more
semanticscholar +1 more source
Journal of the American Society of Nephrology, 2021 BACKGROUND In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens, biomarkers, or both.
A. Ravindran +15 more
semanticscholar +1 more source
Pharmaceutical Biology, 2022 Context Yi Shen An (YSA) is an investigational composite of traditional Chinese medicine (Reference: 2010L000974) for the treatment of renal disease.
Yun-Li Zhao +5 more
doaj +1 more source
Clinical characteristics of males with systemic lupus erythematosus (SLE) in an inception cohort of patients in Ghana [PDF]
Ghana Medical Journal, 2019 Background: Systemic Lupus Erythematosus (SLE) is said to be rare in Sub-Saharan Africa and even rarer in males worldwide. SLE is mostly considered a disease of women, though men may also be affected, and this may lead to a delay in diagnosis in men. The
Dzifa Dey +7 more
doaj +1 more source
Lupus nephritis: clinical presentations and outcomes in the 21st century
Rheumatology, 2020 Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the epidemiology of LN and its clinical presentation have been changing.
M. Gasparotto +4 more
semanticscholar +1 more source
Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis
Journal for ImmunoTherapy of Cancer, 2022 Background Non-invasive biomarkers of immune checkpoint inhibitor-associated acute tubulointerstitial nephritis (ICI-nephritis) are urgently needed. Because ICIs block immune checkpoint pathways that include cytotoxic T lymphocyte antigen 4 (CTLA4), we ...
M. Sise +19 more
semanticscholar +1 more source